…this epigenetic programming is genome-wide, highlighting these genes as a crucial target for future research. EZH2 has been previously demonstrated as a metabolic switch in cancer, allowing the transformation of…
…used to detect diseases like pancreatic cancer and type 2 diabetes. The team performed genome-wide DNA methylation analysis of the thyroid, heart, and brain from 10 cadavers. They were then…
…in maternal blood, monitoring of organ transplants from donor cfDNA in the recipient’s blood, and diagnosis of cancer from tumor cfDNA in so-called “liquid biopsies”. Diseases like diabetes mellitus and…
…(LKSOM) have uncovered an explanation to the longevity conundrum, something they call “age-related methylation drift.” The senior investigator, Jean-Pierre Issa, MD, Director of the Fels Institute for Cancer Research at…
…lifestyle activity. For fourteen years, a team of scientists headed by Hermann Brenner from the German Cancer Research Center in Heidelberg along with their colleagues from the Saarland Cancer Registry…
…proteins are transcribed. Disruptions in epigenetic alterations have been associated with contributing to certain disease states, from breast cancer, to Alzheimer’s, diabetes, and more. Wing et. al lists three reasons…
…use such as heart disease, high blood pressure, cancer, neurological damage, stroke and digestive complications. According to the National Institute on Alcohol Abuse and Alcoholism, binge drinking is a pattern…
…conducted at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), scientists demonstrated the existence of a tunable epigenetic state that sets off increased hematopoiesis to enhance innate immune protection. Published…
…and it’s thought that this “superfood” can epigenetically reduce DNA damage, thereby protecting humans against aging and cancer. Kim, M. et al. (2017). Comparison of Blueberry (Vaccinium spp.) and Vitamin…
…alterations have been studied in oncological contexts, culminating in multiple FDA-approve dcancer therapeutics (Heerboth et. al, 2014). Common epigenetic modifications include acetylation, methylation, sumoylation, alterations to chromatin structure, and, perhaps…
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