DNA Methylation Solves Crimes
…expression. Aberration in DNA methylation has long been linked to diseases such as cancer and exploited as diagnostic biomarkers, but in forensic analysis, the use of DNA methylation as a…
Search Results for transgenerational and dna methylation
Epigenetic Insights for Targeting Alzheimer’s Disease
…effective treatments. DNA Methylation DNA methylation and hydroxymethylation are fundamental processes implicated in AD. DNA methylation involves the addition of a methyl group (5mC) to DNA, which typically results in…
The Epigenetic Marks of Circulating Cell-Free DNA (cfDNA)
Circulating cell-free DNA (cfDNA) are small DNA fragments found circulating in plasma or serum, as well as other bodily fluids. The cfDNA isolated from plasma usually contains fragments of about…
Maybe She’s Born With it, Maybe it’s Epigenetics: 5 Tips for Beauty and Anti-Aging
…much less DNA methylation, referred to as DNA hypomethylation, in the sun-exposed skin of older individuals. This reduced level of DNA methylation, however, was not detected in the older individuals…
Histone Modifications
…23, and 56, methylated at arginine 2 and lysines 4, 9, 27, 36, and 79, and phosphorylated at ser10, ser28, Thr3, and Thr11. Histone H4 is primarily acetylated at lysines…
5 Ways You Might Epigenetically Boost Your Child’s Health Before Birth
…on top of DNA, which can come about due to environment and behavior, might be passed down from generation to generation. Epigenetic mechanisms like DNA methylation or histone modification refer…
New SMRT-BS Method to Revolutionize Quantitative, Multiplexed Targeted Bisulfite Sequencing for Methylation Analysis
…of CpG methylation and methylation abnormalities in DNA via bisulfite sequencing has become overwhelmingly popular – and interest continues to grow. The unparalleled power of next-generation sequencing (NGS) platforms provides…
What is Paleoepigenetics?
…DNA fragments can be analyzed. Early aDNA studies were mostly restricted to mitochondrial DNA (mtDNA). One reason for this is because a cell has hundreds of copies of mtDNA. In…
Type 2 Diabetes Mellitus and Epigenetics
…and results from the complex interaction between genes and environment. Many studies point to epigenetic modifications (DNA methylation and histone modifications) in mediating this interaction. References: Dayeh T, et…
Toxins May Affect Epigenetics Through Multiple Generations
…DNA methylation and its ability to respond to environmental stressors, the distal actions of ncRNA to help integrate the other epigenetic marks and alter gene expression, and the ability of…
