…use such as heart disease, high blood pressure, cancer, neurological damage, stroke and digestive complications. According to the National Institute on Alcohol Abuse and Alcoholism, binge drinking is a pattern…
…conducted at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), scientists demonstrated the existence of a tunable epigenetic state that sets off increased hematopoiesis to enhance innate immune protection. Published…
…lifestyle activity. For fourteen years, a team of scientists headed by Hermann Brenner from the German Cancer Research Center in Heidelberg along with their colleagues from the Saarland Cancer Registry…
…alterations have been studied in oncological contexts, culminating in multiple FDA-approve dcancer therapeutics (Heerboth et. al, 2014). Common epigenetic modifications include acetylation, methylation, sumoylation, alterations to chromatin structure, and, perhaps…
…impact on biological functions, causing any number of health conditions. For instance, certain epigenetic mechanisms are associated with many cancers and other diseases, as well as aging, and psychological disorders….
…dysregulation of transcription is implicated in various cancers, an understanding of this process holds promise for the development of future therapeutic strategies. One of the pioneer transcription factors they studied…
…potentially be in understanding the factors that contribute to—and ways of intervening against—cancers in all types of cells, starting by first comparing healthy tissues versus cancerous ones. Reference: September 9,…
…proteins are transcribed. Disruptions in epigenetic alterations have been associated with contributing to certain disease states, from breast cancer, to Alzheimer’s, diabetes, and more. Wing et. al lists three reasons…
…“In the case of growth in ants, it was the Egfr gene which was determinant. But for other complex traits, whether they are involved in the growth of cancer cells…
…(LKSOM) have uncovered an explanation to the longevity conundrum, something they call “age-related methylation drift.” The senior investigator, Jean-Pierre Issa, MD, Director of the Fels Institute for Cancer Research at…
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