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Epigenetic Imbalance Could Lead To Bipolar Disorder, Schizophrenia

August 13, 2019 Tim Barry

…gene to the healthy development of synapses in the brain. DNA methylation is an epigenetic mechanism involving the addition of methyl groups (CH3) to the 5th cytosine of DNA, which…

epigenetic effect of polyunsaturated and saturated fat

Muffins Reveal Epigenetic Impact of Saturated and Polyunsaturated Fats on Our Bodies

May 23, 2017 Bailey Kirkpatrick

…muffin study to assess epigenetic changes in fat tissue. Specifically, they looked at an epigenetic mark known as DNA methylation and discovered that the epigenetic pattern of over 3,000 genes…

New Single-Cell Bisulfite Sequencing Technique Boosts Epigenetic Research

July 30, 2014 Bailey Kirkpatrick

…mapping the DNA methylation marks within these samples. Current methods that are used to observe epigenetic changes use multiple, pooled cells. By looking at a collection of cells, the individual…

The Benefits of Exercise Goes Epigenome-Deep

January 17, 2023 Natalie Crowley

…methyl group to DNA. Typically, DNA methylation will “turn off” gene expression, but it can also be removed through a process called demethylation. When the Skinner team compared the cheek…

Researchers Discover Disease Causes Abnormal Chromatin Packaging in Cells

August 30, 2022 Natalie Crowley

…Their findings were published in the August 22 issue of Nature Biomedical Engineering. Epigenetic processes like DNA methylation, histone methylation, and histone acetylation control the compaction or accessibility state of…

m6A Editing: Harnessing CRISPR-Cas for Programmable RNA Modification

November 8, 2022 Mike Spelios

…S, Ries RJ, Jaffrey SR. Reading, writing and erasing mRNA methylation. Nat Rev Mol Cell Biol. 2019;20(10):608-624. doi:10.1038/s41580-019-0168-5 Hastings MH. m(6)A mRNA methylation: a new circadian pacesetter. Cell. 2013;155(4):740-741. doi:10.1016/j.cell.2013.10.028 Niu Y,…