Toxins May Affect Epigenetics Through Multiple Generations
…the differential DNA methylation regions (DMRs) and non-coding RNA (ncRNA) to see if such epigenetic marks were altered between mice lineages exposed to DDT and those that were not. The…
Search Results for dna methylation
Air Pollution Could Alter Tags on DNA and Increase Risk for Neurodegenerative Disease
…team of researchers set out to investigate the role of oxidative stress and DNA hydroxymethylation caused by particulate matter from air pollution, in the development of neurodegenerative disease. 5-hydroxymethylcytosine (5-hmC)…
Poor Socioeconomic Status May Leave Epigenetic Mark on Gene Linked to Depression
…to DNA, typically suppressing gene expression. In general, increased DNA methylation of gene promoters has been linked to stressors, including low SES. Furthermore, recent studies have shown that DNA methylation…
Epigenetic Study Finds New Potential Drug Targets for Asthma and Allergies
…which had not previously been done before. The researchers investigated DNA methylation, or the process by which a methyl group is added onto DNA which can often silence certain genes….
Fathers’ Teenage Weight May Leave an Epigenetic Mark on Future Children
…changes in gene expression that affect how genes work without changing the DNA sequence itself. One common epigenetic mechanism is DNA methylation, which helps regulate whether certain genes are more…
B Vitamins Protect Against Harmful Epigenetic Effects of Air Pollution
…after each experiment. Overall, they found that the fine particles induced methylation changes in genes involved in mitochondrial oxidative energy metabolism. Air pollution was shown to disturb DNA methylation profiles,…
Seed Dormancy Stems from the Mother Plant Via Epigenetics
…study, the team discovered that the paternal allele of ALN is silenced at the promoter region of the gene by biochemical alterations called methylations, more specifically non-canonical RNA-directed DNA methylation…
Epigenetic Clock Destines Some to Age Faster Regardless of Lifestyle
…many links researchers have found between epigenetics and age will become even more crucial. If you’ve had your DNA sequenced, you can follow Horvath’s DNA methylation age tutorial to calculate…
A Western Diet May Adjust Epigenetic Marks on Children’s DNA and Damage The Nervous System
…a regular diet. Several analyses were carried out using tissue samples of offspring, including DNA methylation bisulfite sequencing, real-time PCR (RT-PCR), and ACE2 specific activity assays. Exposure to this high-fat…
Natural Compounds in Grapes Could Lead Us to An Epigenetic Treatment for Depression
…PBMC IL-6 expression by inhibiting DNA methylation of the IL-6 genes at the CpG-rich sequences of IL-6 introns 1 and 3. The well-known epigenetic mechanism DNA methylation was reduced by…
