The Epigenetics of Chronic Kidney Disease

January 15, 2019 Adam Alonzi

Chronic kidney disease (CKD) affects 20 million people in the United States and an estimated 8 to 16 percent of the world’s population. It is known that anomalous DNA methylation, aberrant histone alterations, and changes to microRNA expression all contribute to its pathogenesis. These epigenetic factors are crucial to the development and proper functioning of the kidneys. The manner and extent to which these factors modulate inflammation, fibrosis, and the transition of mesenchymal to epithelial cells is still being elucidated. The [more…]

Curcumin May Alleviate Liver Damage Caused by Drug-induced Epigenetic Changes

November 20, 2018 Natalie Crowley

For centuries, people all around the globe have known about the health benefits of herbs and spices. One spice, in particular, stands out not only for its bright yellow color but also for its potent healing powers. This wonder spice is Curcuma longa, commonly known as turmeric, and it belongs to the ginger family. Traditionally used in Indian cooking as a main ingredient in curry powder, this spice is also used to make medicine. Numerous studies have promoted turmeric as [more…]

Epigenetic Mark Found in Microbiome Could Help Prevent Digestive Disorders

September 25, 2018 Tim Barry

Maintaining a healthy diet can be incredibly difficult to do, especially with the temptations of junk food, alcohol, and sweets. Often times we are in a rush to get to plans that we’ve made, or go grab a drink after work, and we forget to prioritize putting nutritious foods in our bodies. As a result, most of us follow a western diet in our everyday lives, because the foods are more readily available (and seem to taste better). This diet [more…]

Epigenetics of Breastfeeding: 4 Diseases and Disorders That Breast Milk Could Protect Against

August 2, 2018 Janeth Santiago Rios

Many people believe that breastfeeding is the best gift a mother can offer to her child. It has lots of benefits, not only because breast milk contains the right amount of nutrients, but also because it’s packed with lots of antibodies and biologically active compounds that play a key role in boosting a baby’s immune system. We have already seen how maternal nutrition and lifestyle can shape the development and future health of a baby via epigenetic mechanisms. Among many [more…]

Epigenetics, Nutrition, and Our Health: How What We Eat Could Affect Tags on Our DNA

May 15, 2018 Bailey Kirkpatrick

Many of us are familiar with the foods that damage our bodies – they slow our metabolism, might add a few pounds, and stiffen our arteries. But what if certain food items could help or harm us in a place we may never have considered – like our DNA? A developing field called nutriepigenomics examines the connection between diet and chemical marks that can be attached to or removed from our DNA, thereby turning genes on or off. Many new [more…]

Epigenetics Clues to Obesity and How Lifestyle Changes Could Modify Your Epigenetic Profile

May 1, 2018 Estephany Ferrufino

Adiposity is a condition of being severely overweight or obese and it has numerous connections to epigenetics. Understanding more about the epigenetics underlying obesity could help to introduce preventions based on lifestyle changes which may be able to modify our epigenetic marks and improve health. A rough measure of obesity is body mass index, BMI, which can be calculated by dividing one’s body weight in kilogram by the body height in square meters. According to the World Health Organization (WHO) [more…]

Early Epigenetic Nutrition ‘Memory’ Could Program You for Obesity Later in Life

April 24, 2018 Bailey Kirkpatrick

For decades, we’ve known how important it is to receive proper nutrition during early stages of life. Nutritional experiences in the beginning of development can set the stage for many things, including body weight, and can even affect the risk of obesity as we get older. Recent research supports the idea that poor nutrition at the beginning of pregnancy or while a baby is nursing can be stored as molecular epigenetic “memory” on the child’s genome, potentially setting them up [more…]

EpigenCare Pioneers Personalized Skincare Based on Your Unique Epigenetic Signature

March 15, 2018 Bailey Kirkpatrick

Pinpointing factors that make a person unique could shift the entire landscape of how we attend to our health – from exercise plans to custom diets and even skincare regimens. The concept of personalization has pierced the bubble of the prevailing “one size fits all” mentality, deflating the flawed notion that what works for the majority will likely work for anyone. When it comes to our bodies’ largest organ, and caring for it effectively, epigenetics may provide an answer. Our [more…]

Maybe She’s Born With it, Maybe it’s Epigenetics: 5 Tips for Beauty and Anti-Aging

February 20, 2018 Bailey Kirkpatrick

We might say a beautiful woman is born with her looks or that she was endowed with good genes. But what if some of her beauty comes from reversible marks on top of her genes? The epigenetic tags on her DNA might be contributing to her glowing skin, young complexion, and silken hair. Interestingly, there may even be ways in which simple lifestyle changes could adjust these epigenetic tags, modulating the expression of certain genes that promote beauty and health. [more…]

Natural Compounds in Grapes Could Lead Us to An Epigenetic Treatment for Depression

February 6, 2018 Bailey Kirkpatrick

Recent research suggests that our diet and lifestyle can change the expression of our genes. This occurs by adjusting epigenetic marks on top of our DNA without actually making any changes to the underlying genetic sequence. For example, blueberries were found to epigenetically reduce DNA damage and drinking green tea may turn some genes on or off in women. In a new epigenetic study published in Nature Communications, researchers from Icahn School of Medicine at Mount Sinai have identified two [more…]

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