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Epigenetics May Be Involved in Noise-Induced Hearing Loss

February 16, 2021 Vered Smith

Noise-induced hearing loss (NIHL) affects about 40 million adults in the U.S aged 20-69 (1). As the name suggests, it is a loss of hearing due to loud noise exposure. The louder the noise and the more often a person is exposed to it, the more it harms their hearing. Although it is the second most likely reason of hearing loss (the first being age), there is currently no cure, and we don’t fully understand how loud noises biologically cause [more…]

Epigenetically Awaking Ancient Parts of Our DNA to Fight Cancer

November 3, 2020 Natalie Crowley

Buried within our DNA, there exists a vast amount of dormant genetic material – a remarkable percentage of which consists of ancient inserted elements that have found their way into our genome, only to be silenced for millions of years. While the origins of most of these obsolete retroelements are not fully known, their inactive status is epigenetically controlled. It has been suggested that “turning on” these parts of our genome could be useful, especially in fighting off certain diseases [more…]

Pandemic-Related Lifestyle Changes Could Affect the Epigenetic Regulation of Your Skin

September 22, 2020 Clarissa Li

The COVID-19 pandemic has impacted the entire world, and many countries have been devastated by the fallout. As this virus swept the world, it has not only changed many aspects of the global economy but also has transformed the way we live our everyday lives. The skin is one of the major body parts that have been impacted by the coronavirus. It’s apparent that frequent usage of personal protective equipment and excessive personal hygiene could trigger different skin conditions. These skin conditions [more…]

A Look Into the Epigenetics of a Coronavirus Infection

March 10, 2020 Natalie Crowley

Emerging viral infections pose a major threat to global public health. In the last two decades, the world has dealt with several fatal outbreaks from the Swine Flu to Ebola to Zika infections and more. The latest to appear is COVID-19, which emerged in December in Wuhan, China and spread quickly around the globe. Although this disease is new, the virus itself is not entirely unknown. It’s actually a type of coronavirus (CoV) –one that is similar to SARS-CoV and [more…]

Epigenetics May Be Reason For Ineffective Depression Treatment

February 25, 2020 Andrea P

According to the World Health Organization (WHO), over 264 million people worldwide are affected by depression at any point in time. Each year, about 800,000 people die by suicide, which is also the second leading cause of death in people between the ages of 15 and 29 years old. Depression is a crippling illness that can affect anybody at any time. Understanding the molecular and genetic factors at play in depression is critical to developing effective treatment methods to address it [more…]

Aspirin May Epigenetically Help Prevent Breast Cancer in Some, Enable it in Others

September 17, 2019 Andrea P

Widely lauded for its anti-inflammatory effects, aspirin is often resorted to in regular doses for disease prevention. For example, previous research studies have supported the idea that women who regularly take aspirin and then are diagnosed with breast cancer may live longer, which has perpetuated this as a medical recommendation. However, the latest study out of the University of North Carolina’s Gillings School of Global Public Health shed light on a subgroup of breast cancer patients for whom regular use [more…]

woman sitting in wheelchair, her daughter hugging her

Potential Epigenetic Avenues for ALS Relief

June 11, 2019 Tim Barry

Amyotrophic lateral sclerosis (ALS), perhaps more commonly known as Lou Gehrig’s disease, is a devastating neurological disease that ultimately leads to death. This disease eats away at nerve cells, causing death to the motor neurons in the brain and spinal cord, resulting in the loss of muscle function and eventual paralysis and respiratory failure. ALS occurs in 2 main types: Sporadic and Familial. Sporadic ALS is the most common form, and it occurs in individuals in their late 50’s/early 60’s [more…]

Epigenetics Involved in Improving COPD Treatment

April 16, 2019 Natalie Crowley

Breathing can be difficult for millions of people around the world who have COPD. While there are available treatments that can reduce the symptoms of this condition, one major barrier to their effectiveness is corticosteroid resistance. The mechanisms that contribute to this type of resistance are unknown, but recent evidence suggests that certain epigenetic factors may play a role. COPD (or chronic obstructive pulmonary disease) is a term used to describe progressive lung diseases including chronic bronchitis and emphysema. Long-term [more…]

Man holding back kidney pain epigenetics

The Epigenetics of Chronic Kidney Disease

January 15, 2019 Adam Alonzi

Chronic kidney disease (CKD) affects 20 million people in the United States and an estimated 8 to 16 percent of the world’s population. It is known that anomalous DNA methylation, aberrant histone alterations, and changes to microRNA expression all contribute to its pathogenesis. These epigenetic factors are crucial to the development and proper functioning of the kidneys. The manner and extent to which these factors modulate inflammation, fibrosis, and the transition of mesenchymal to epithelial cells is still being elucidated. The [more…]

Curcumin May Alleviate Liver Damage Caused by Drug-induced Epigenetic Changes

November 20, 2018 Natalie Crowley

For centuries, people all around the globe have known about the health benefits of herbs and spices. One spice, in particular, stands out not only for its bright yellow color but also for its potent healing powers. This wonder spice is Curcuma longa, commonly known as turmeric, and it belongs to the ginger family. Traditionally used in Indian cooking as a main ingredient in curry powder, this spice is also used to make medicine. Numerous studies have promoted turmeric as [more…]

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