The concept of DNA library preparation after bisulfite conversion of DNA was originally introduced by Miura et al. (Nucleic Acids…
Post-translational modifications are well known for their influence on protein stability, enzymatic functions, as well as protein:protein interactions. At the…
Recent developments in DNA methylation analysis technologies have made it crucial for researchers to understand which tool is optimal for…
A new single-cell bisulfite sequencing (scBS-seq) technique that can advance epigenetic experiments has been developed by researchers from BSRC-funded Babraham…
Over the past decade significant advances have been made in methylation profiling technology allowing for highly specific and accurate information…
Every epigenetics scientist knows that chromatin immunoprecipitation (ChIP) is a valuable technique for studying protein-DNA interactions. They also know that…
Researchers rely on high quality antibodies to perform successful chromatin immunoprecipitation (ChIP) experiments. When investigating the protein-DNA interaction of interest,…
The following histone extraction protocol was written by scientists at Epigentek and is a recommended and optimized procedure for their…
Hematopoietic stem cells (HSCs) are rare bone marrow cells that have self-renewal capability and are multipotent. Upon differentiation, HSCs become…
Messenger RNA (mRNA) is a single-stranded RNA molecule that is essential in mediating the transfer of genetic information from DNA…