For The Scientist

The Epigenetic Marks of Circulating Cell-Free DNA (cfDNA)

Circulating cell-free DNA (cfDNA) are small DNA fragments found circulating in plasma or serum, as well as other bodily fluids.…

8 years ago

Histone variant H2A.Z underlies inactivation of activity-dependent gene expression in learned behavior

Over the past decade discoveries about the role of epigenetic mechanisms in learning and memory have changed the way scientists…

8 years ago

New Method Simultaneously Profiles Methylome and Transcriptome in the Same Single Cell

A new single-cell genomics protocol that is potentially transformative for epigenetics research has been developed by scientists in the UK…

8 years ago

ChIP Reveals Unexpected Insight into Flatworm Tissue Regeneration and Histone Modifications

Planaria, or flatworms, are often used as a model organism to investigate the fascinating process of how tissues and organs…

8 years ago

New SMRT-BS Method to Revolutionize Quantitative, Multiplexed Targeted Bisulfite Sequencing for Methylation Analysis

Bisulfite sequencing offers researchers a profound look into the epigenome and the methylation status of genes. A significant driving force…

9 years ago

Collecting & Analyzing Libraries For Chromatin Immunoprecipitation (ChIP)

Editor’s Note: At the author’s request on August 20th, 2015, revisions to this article were made following careful consideration. All changes…

9 years ago

A Starter Chromatin Immunoprecipitation (ChIP) Protocol

Editor’s Note: At the author’s request on August 20th, 2015, revisions to this article were made following careful consideration. All changes…

9 years ago

Preparation for Chromatin Immunoprecipitation (ChIP)

Editor’s Note: At the author’s request on August 20th, 2015, revisions to this article were made following careful consideration. All changes…

9 years ago

Simple Tweak Could Make Post-Bisulfite Library Preparation Suitable for RRBS

The concept of DNA library preparation after bisulfite conversion of DNA was originally introduced by Miura et al. (Nucleic Acids…

9 years ago

Introducing O-GlcNAc – The Latest Addition to the Orchestra of Epigenetic Modifications

Post-translational modifications are well known for their influence on protein stability, enzymatic functions, as well as protein:protein interactions. At the…

9 years ago