The scientists at MIT describe an approach for efficient targeted demethylation of specific CpGs in human cells using fusions of…
5-methylcytosine is found in the context of paired symmetrical methylation of a CpG site. In normal somatic cells, most CpG…
In their studies, the scientists at Beckman Research Institute of City of Hope demonstrated that Ten eleven translocation (TET) enzymes…
Scientists at Epigentek developed a series of new products for DNA library preparation used in next generation sequencing analysis of…
The scientists from A*STAR's Institute of Medical Biology (IMB) and Institute of Molecular and Cell Biology (IMCB) developed a novel…
To form chromatin, DNA is tightly wrapped around nuclear proteins called histones. The repeating DNA-histone complex, which consists of 146…
In human DNA, 5-methylcytosine is found in approximately 1.5% of genomic DNA. In somatic cells, 5-mC occurs almost exclusively in…
Scientists from Japan developed methylation-specific fluorescence in situ hybridization (MeFISH) for microscopic visualization of DNA methylation status at specific repeat…
San Diego-based Illumina, Inc. doubles the sequencing output of its benchtop sequencer MiSeq to 15 gigabases (Gb) by increasing the…
Currently, DNA methylation is one of the most broadly studied and well-characterized epigenetic modifications associated with gene silencing. The biological…