Explore the many ways in which different types of food and drink have potential to influence epigenetic marks on DNA and, ultimately, health outcomes. Learn how broccoli may be able to epigenetically reduce cancer risk, how an assortment of herbs could boost health, and even the ways a high fat, low carb diet may be able to boost mental ability. This collection of cutting-edge nutriepigenetic research studies aims to break down complex dietary epigenetic findings and understand its potential application in our daily life.
Check out our comprehensive e-book Epigenetics in Life: What We Eat to learn more about how different foods influence health.
Scientists at McGill University, Canada reported that folate deficiency in a father’s diet could increase birth defects in the offspring by altering sperm epigenome. These defects include craniofacial and musculoskeletal malformations. The scientists fed male mice either a folate-deficient or folate-sufficient diet throughout life and then performed genome-wide DNA methylation analysis and subsequent functional analysis to identify differential methylation in sperm of genes implicated in development, and chronic diseases such as cancer, diabetes, autism and schizophrenia. They found that >300 [more…]
Cellular reprogramming of somatic cells to a pluripotent state (an undetermined state in which a cell is capable of differentiating to all of the various cell types of the body) is accompanied by several epigenetic changes including genome-wide resetting of DNA methylation status. Vitamin C, an essential nutrient for humans, is involved in several metabolic pathways and in the prevention of conditions such as scurvy. Vitamin C was recently found to promote the generation of induced pluripotent stem cells (iPSCs) [more…]