Articles that explore the connection between epigenetics and diseases and disorders, including cancer, cardiovascular disease, diabetes, autoimmune disease, and more.

The Epigenetics of Chronic Kidney Disease

January 15, 2019 Adam Alonzi

Chronic kidney disease (CKD) affects 20 million people in the United States and an estimated 8 to 16 percent of the world’s population. It is known that anomalous DNA methylation, aberrant histone alterations, and changes to microRNA expression all contribute to its pathogenesis. These epigenetic factors are crucial to the development and proper functioning of the kidneys. The manner and extent to which these factors modulate inflammation, fibrosis, and the transition of mesenchymal to epithelial cells is still being elucidated. The [more…]

DNA Methylation Study Provides Insight for Treating Brain Cancer

December 11, 2018 Tim Barry

Receiving the diagnosis of a brain cancer is undoubtedly disastrous news that nobody wants to hear for themselves or their loved ones. Although significant advances have been made to understand and treat many cancers, the mortality rate remains high for cancers of the brain.  New research, however, may be shedding light on one form of brain cancer by investigating the epigenetic character of the disease. Glioblastoma is the most common and deadliest type of brain cancer in adults. It’s considered [more…]

Epigenetic Insights on Nutrition, Hormones and Eating Behavior

December 4, 2018 Janeth Santiago Rios

It is widely acknowledged that alterations of the intrauterine and early postnatal nutritional and hormonal environment can make individuals more susceptible to the development of diseases in later life, a phenomenon clearly explained by epigenetics. We know that what the mother eats during pregnancy can increase the risk of the baby becoming obese as an adult, among other several health disorders. However, the link between these two is much more complex than we thought, as epidemiological and animal studies have [more…]

Depression Could Severely Increase Epigenetic Aging

November 27, 2018 Tim Barry

Depression can certainly take its toll on a variety of physical and mental processes, so it’s no surprise that major depression often coincides with a shortened lifespan. Now scientists are finding that there may be more to this link than just purely an unfortunate coincidence. According to a new study, major depression disorder (MDD) may actually speed up the aging process on a molecular level and the results illuminate a significant epigenetic mechanism. MDD is a very common mental disorder [more…]

Curcumin May Alleviate Liver Damage Caused by Drug-induced Epigenetic Changes

November 20, 2018 Natalie Crowley

For centuries, people all around the globe have known about the health benefits of herbs and spices. One spice, in particular, stands out not only for its bright yellow color but also for its potent healing powers. This wonder spice is Curcuma longa, commonly known as turmeric, and it belongs to the ginger family. Traditionally used in Indian cooking as a main ingredient in curry powder, this spice is also used to make medicine. Numerous studies have promoted turmeric as [more…]

Natural Compound in Garlic Uses Epigenetics to Fight Ovarian Cancer

November 13, 2018 Natalie Crowley

Garlic has been used in food and as medicine since ancient times. Considered a superfood for its role as a health promoter, this small, pungent vegetable is widely used today to prevent and treat numerous conditions from the common cold to heart disease, cancer, and more. Now new research is confirming garlic’s medicinal ability, finding that it contains a powerful substance that acts epigenetically to halt the growth of ovarian cancer. There are numerous nutrients in garlic that are beneficial [more…]

Fluoride’s Epigenetic Effect on Bone Development

November 6, 2018 Natalie Crowley

When it comes to dental health, fluoride is considered a champion against tooth decay. It’s in just about every brand of toothpaste, even added to our drinking water here in the US. But fluoride is a chemical and too much of it can be toxic. Excessive exposure to fluoride has been shown to cause adverse health effects, many of which cannot be corrected.  While several studies have examined chronic fluoride exposure and its link to certain conditions, little is known [more…]

Scarred For Life: The Epigenetics of Fear

October 30, 2018 Lisa Fox

When someone is truly scared or traumatized, they might say they were “scarred for life”. While this might seem like a metaphor, recent studies show that fear might actually leave permanent epigenetic marks on your DNA, marks you could potentially pass down to your children or grandchildren. Fear is a basic biological process. In their lifetime everyone has experienced it in one form or another, and we are all afraid of different things.  From fear of physical things like spiders, [more…]

Nutrition May Have an Epigenetic Impact on Early Puberty in Girls

October 24, 2018 Tim Barry

Maintaining proper nutrition is a very important factor in living a long, healthy life. Foods that have little nutritional benefits have become easier to get our hands on, so the emphasis on proper nutritional health has become a fleeting priority for some people and their families. As a result, most individuals have inadvertently accepted the  western diet, rich in empty carbs, red meats and saturated fats, as their everyday diet. Diet can also impact a person’s epigenetics, and people can [more…]

Red Wine Components May Epigenetically Help Prevent Breast Cancer Growth

October 16, 2018 Natalie Crowley

Pink may be the color for breast cancer awareness month, but when it comes to reducing your risk for the disease; the color red makes a good choice. New research has found that certain chemicals highly concentrated in red wine may hinder breast cancer cell growth, as well as influence a person’s epigenetics. Breast cancer has been said to be the single most important health crisis women face today. Despite advances in modern medicine, 180,000 new cases of invasive breast [more…]

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