How Epigenetics is Improving Our Understanding of Domestication in Animals
…the size of the Junglefowl and lay a great deal more eggs that are larger and varied in color. They are also less fearful and have adapted to eating and…
Search Results for transgenerational and dna methylation
Accessing Histone PTMs: Insights Into the Methods Used for Their Assessment
…chromosomes, histones have been revealed to support critical cellular processes (transcription, DNA replication, and DNA repair, to name a few) via diverse PTMs that regulate their interactions with DNA and other nuclear proteins….
Down a Path of Epigenetic Destruction: Smoking Cigarettes Adjusts Critical Marks on DNA
…previously shown that EZH2 and its effects are indicators that come before abnormal DNA methylation in genes. DNA methylation is a popular epigenetic mechanism that entails the addition of a…
Bolstering Your Defenses Against COVID-19: An “Epigenetic” Diet
…by methylation plays an important role in virus replication, assembly, and maturity. For example, the 5′ cap of viral RNA is produced by methylation of the N7-guanosine and 2′-O-adenosine positions….
A Novel Role for RNA Methylation (m6A) in the DNA Damage Response
…of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family and members of the poly (ADP-ribose) polymerase (PARP) family, and allows the cells to recognize the DNA damage and facilitate recruitment and…
The Epigenetics of Father’s Day: 3 Little Known Reasons to Thank Your Dad
…genotype. “Epi-” means “above” or “on top of” and these chemical modifications, such as DNA methylation or histone modifications, occur to the DNA and impact gene expression without actually altering…
A Starter Chromatin Immunoprecipitation (ChIP) Protocol
…proteins and frees the DNA to diffuse into solution. The DNA libraries decrosslink at 65 degrees for eight hours. The libraries are cleaned up via column preps or DNA precipitation….
Paternal Exercise Epigenetically Enhances Expression and Inheritance of a Key Gene Involved in Learning and Memory
…and histone acetylation as having opposing effects: DNA methylation represses gene expression, while histone acetylation promotes gene expression. A class of enzymes called DNA methyltransferases (DNMTs) catalyzes methylation of DNA…
Affectionate Moms with Depression May Epigenetically Buffer Their Child from Stress
…Select the ideal DNA bisulfite conversion kit and begin your DNA methylation research today! Previous research has demonstrated that there’s often an increase in DNA methylation and a decrease in…
The Epigenetics of Sleep: 3 Reasons to Catch More Zzz’s
…the levels of DNA methylation associated with circadian gene loci, immune system- and inflammation-related gene loci. Overall, these studies illustrate that sleep and epigenetics go hand-in-hand. Improving sleep can help…
