Heat Stress Upsets the Epigenome of Dairy Cattle Offspring
…animal losses each year. Not only are the cows negatively impacted, but calves born to pregnant dams exposed to heat stress are also affected….and for years later with reduced immune…
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Using Epigenetics to Combat a Terrible Neglected Tropical Disease
…the cycle starts all over again. Other eggs can become trapped in body tissues, causing immune reactions and progressive damage to organs. Without treatment, schistosomiasis can persist for years, resulting…
Does DNA Methyltransferase Control the Brain’s ‘Gender’?
…behavior, they were males. It was fascinating to see this transformation.” In a separate study, Professor McCarthy and Nugent also discovered that microglia, or inflammatory immune cells, may be involved…
How Aging Makes Skin More Sensitive Through Epigenetic Changes
…to balance after stress. Free radicals and inflammatory signals can affect cellular pathways involved in repair, immune response, and tissue maintenance. If these regulatory systems become less stable with age,…
Epigenetic Signature Found in Blood Predicts Chances of Getting Breast Cancer
…supports that changes in the epigenome of immune cells are crucial to cancer progression. The immune system may be unable to prevent breast cancer from forming because the signature may…
Cannabis Use Leaves a Lasting Mark on the Epigenome
…changes crucial for fetal development. This study’s focus on DNA methylation related to high-potency cannabis use expands our understanding of how cannabis may influence genes linked to immune and mitochondrial…
Epigenetics Explains Increased Drug Resistance in Malaria Parasite
…uncanny ability to mutate frequently in order to survive and propagate. In the presence of an infection, the resistant mutations can evade the body’s immune system, as well as other…
Epigenetic Factors Determine the Characteristics of B-Cells
Most people know antibodies as the “warriors” of our immune system, helping us fight off invading pathogens. But not all antibodies are made for this purpose. Some perform necessary maintenance…
Epigenetic Mechanism Shows Promise in the Fight Against HIV Latency
HIV is a chronic viral infection that attacks the immune system, eventually incapacitating its ability to fight infection leaving the person vulnerable to the development of AIDS, which often leads…
Epigenetic Drugs That Fight Cancer Also Show Promise as Antivirals
…of host immune cells to the sites of infection,” said Dr. Kristie. After analyzing the transcriptome, the researchers found that the epigenetic drugs caused numerous antiviral and stress pathways that…
