…via DNA methylation. We have also written several articles that show how viruses use epigenetics to evade the immune system and how epigenetic cancer therapies are becoming more mainstream. Indeed, one…
…cancer. Inside the cell’s nucleus, DNA tightly winds itself around histones, a specialized type of protein responsible for the formation of chromatin. Typically, histones package the DNA so tightly that…
…genetic information encoded in our DNA. Despite containing identical DNA, different cells express distinct sets of genes, sculpting their unique identities and functions. This phenomenon, influenced by epigenetics, involves molecular…
…and Methylation system Database (WERAM). WERAM is a comprehensive database containing integrated information on the writers, erasers, and readers of histone acetylation and methylation. Namely writers are the enzymes that…
…methylation modification. Over 5,000 different mRNA molecules contain m6A, subsequently implying widespread effects on gene expression. Epigentek’s new technology and product essentially enables researchers to study m6A-based RNA methylation whom…
…lacking this methylation produce a much higher innate immune response?” Upon reviewing the cellular signaling pathways involved, it became evident that m6A methylation makes the virus able to hide from…
…proteins. Histone modification is a key epigenetic mechanism and is involved in many various biological processes including gene regulation, DNA repair, and chromosome condensation. Methylation, acetylation, and phosphorylation are just…
…Drug Resistance A new generation of therapeutics, epigenetic cancer therapeutics (epidrugs), targets differences in methylation or acetylation of DNA sequences that alter transcription of genes involved in cancer and drug…
…that affect gene and/or protein expression in neurons at the central level. Epigenetic factors like DNA methylation, histone modification, and chromatin remodeling control gene expression and are triggered by environmental…
…the researchers also found an increase in H3K27me3 marks on the DNA, as well as an increased level of DNA methylation at the promotor and coding regions of the PTEN…
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