Histone Modifications
…in cancer cells. HDAC inhibitors are currently being developed as anticancer agents.2 Getting Started the Easy Way Extract your nuclear proteins from your sample of interest, then utilize an ELISA-like…
Search Results for cancer
DNA Hydroxymethylation Regulates Gene Expression of Cancer-Causing Epstein-Barr Virus
…familiar with – infectious mononucleosis, or mono. This virus, when in its latent form in humans, can also lead to cancer of the upper-throat, or nasopharyngeal carcinoma (NPC). Researchers from…
Epigenetic Drugs That Fight Cancer Also Show Promise as Antivirals
…of repressive H3K27me3-enriched chromatin domain. Several EZH2/1 inhibitors are presently in the development and evaluation process in clinical trials for cancer. “Some specific cancers are based on “gain of function”…
Epigenetics: Fundamentals
…genetic and epigenetic errors can transform a normal cell into an invasive or metastatic tumor cell. Cancer. Cancer was the first human disease to be linked to epigenetics. Studies performed…
Epigenetic Mechanism Found May Combat Cancer and Aging
…and the cells no longer function properly. The results can cause dormant cells that no longer divide, as in aging, or uncontrolled cell division, as in cancer. To better understand…
DNA Methylation and Glucocorticoid Resistance Offers Clues to Improve Cancer Drugs
…discovery could help create more effective cancer drugs and improve the treatment of many autoimmune related diseases. The researchers looked at a certain type of steroid hormones involved in the…
DNA Methylation Editing: Expert Insights into the Technologies, Challenges, and Future Perspectives
…engineered to fight cancer (CAR-T cells), rather than to change the cancer cells themselves. In this way, epigenetic editing can be used to enhance this cell-based anticancer therapy.” Key challenges…
Circadian Rhythms, Epigenetics and Disease
…cancer cells. In addition to CLOCK, BMAL1 has also been reported to be involved in cancer. The PER repressors of the circadian clock have also been linked to cancer. Recent…
HDAC Inhibitor Could Sharpen Memory and Treat Cancer
New research has found that a histone deacetylase (HDAC) inhibitor drug used to treat cancer could also help sharpen memory and improve one’s ability to learn a new language. It…
The Epigenetic Benefits of Your Thanksgiving Feast
…State of the Art and Future Challenges. Natural Products in Cancer Prevention and Therapy. 329: 73-132. Davis CD, Ross SA. (2007). Dietary components impact histone modifications and cancer risk. Nutr…
