Switching Off Genes with A New CRISPR Epigenetic Editing Tool
…to be turned off without altering the DNA sequence. Traditional CRISPR methods involve editing the DNA using a protein found in bacterial immune systems along with single guided RNA to…
Search Results for immune
Cataloging DNA Methylation & Gene Expression in Children
…& neurological disorders, autoimmune diseases, as well as aging. The current study referenced data from the Human Early Life Exposome (HELIX) project and examined blood samples from 832 children,…
Epigenetic Mark Found in Microbiome Could Help Prevent Digestive Disorders
…diagnosed with IBD. They found increased levels of histone methylation in genes associated with metabolism, immune regulation, and cell signaling, potentially uncovering the underlying mechanisms that could cause severe inflammation…
Certain Ethnic Groups May Epigenetically Age Slower
…investigating the blood, the researchers were able to determine how healthy their immune systems were. According to the epigenetic clock, female Latino’s biological age was as nearly two and a…
Maybe She’s Born With it, Maybe it’s Epigenetics: 5 Tips for Beauty and Anti-Aging
…of the immune system. It’s also thought to play a significant role in collagen and elastin breakdown. Since our diet is closely intertwined with aging, eating the proper food could…
Histone mimicry: How a SARS-CoV-2 protein functions as an H3 mimic to disrupt host cell epigenetic regulation
…development of novel diagnostics and suitable therapies. Although reports suggest that SARS-CoV-2 can dysregulate the host’s gene expression and innate immune response, the underlying mechanism has remained somewhat elusive, until…
The Epigenetics of Chronic Kidney Disease
…deacetylase inhibitors (HDAC-i’s) in part regulate immune response, it is of little wonder that they also contribute to fibrosis. The expression of Connective Tissue Growth Factor (CTGF) can be influenced…
Chromatin Immunoprecipitation Study Supports HDAC Inhibitor as Possible Lung Cancer Treatment
…of anticancer effects, including tumor cell apoptosis, cell cycle arrest, differentiation, senescence, modulation of immune responses, and altered angiogenesis,” explained Dr. Chun. Their results indicated that “HDAC inhibitor treatment induced…
Histone Modifications – Regulators of Viral Infection
…with the H3 histone variant H3.3 containing repressive K9me3. The innate immune DNA sensor IFI16 employs an alternate course of action: the direct recruitment of H3K9-methylating enzymes to viral DNA…
4 Epigenetic Tips to Improve Health
…epigenetics and the choices we make as well as the environment in which we live. For example, getting enough sleep could epigenetically benefit our immune and metabolic functioning.1 Exercising has…
