Betaine Intake During Pregnancy May Epigenetically Effect Transcription

May 26, 2020 Brandon Eudy

Betaine is a methyl-donor nutrient that can be obtained through the diet and is especially rich in spinach, beets, and whole-wheat foods. Alternatively, betaine can be synthesized from choline obtained through other dietary sources. Methyl donor nutrients provide precursors for methyl groups used in important biological processes including methyltransferase enzymes which regulate DNA methylation. There is currently great interest in better understanding how dietary methyl donors can effect epigenetics, and whether changes in DNA methylation can be carried from generation [more…]

Epigenetics Could Explain Why COVID-19 Affects People Differently

May 12, 2020 Fanni Daniella Szakal

Disclaimer: One of the reference papers has not yet been peer-reviewed. The COVID-19 pandemic spread around the globe in a matter of months, leaving devastating human health and economic consequences in its wake. From a viral point of view, this incredible success is the result of a careful balance between its deadliness and contagiousness. While the number of deaths is nearing the 300,000 mark as of May 2020, many who are infected show only mild symptoms or no symptoms at [more…]

Premature Birth Can Leave Epigenetic Marks on Child’s DNA

May 6, 2020 Andrea P

According to the World Health Organization (WHO), the annual figure for preterm births is 15 million babies, which is somewhere in between 5% and 10% of all births worldwide. These babies are born before 37 weeks’ gestation, and are known to be at higher risk for health complications at birth that include: respiratory issues, eye problems, and even neurodevelopmental disorders. But what are the specific molecular mechanisms that drive these health problems? After all, once born, premature babies are given [more…]

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