Therapeutic Targeting of Histone Modifications: Insights from the Experts
This article was first published by EpigenTek. It would be a near impossible feat for the human genome, consisting of some 3 billion bases, to fit within its relatively miniscule cellular accommodations if not for the help of a family of very critical DNA-interacting proteins. Histones are the primary protein constituent of chromatin, forming complexes with DNA to compact our rather expansive genetic material for efficient nuclear organization. But make no mistake, these protein “spools” are not merely packaging units [more…]
