Most Dangerous Lifestyle Activity Uncovered in New Epigenetic Mortality Risk Profile

March 28, 2017 Bailey Kirkpatrick

Aging and mortality has been a fascinating topic of interest recently, particularly in the field of epigenetics. What are the chemical DNA markers of age? Can we look at someone’s epigenome to determine their risk for death? Could we reverse these epigenetic tags to restore youth or undo the pesky physical characteristics and diseases that come with getting old? And are there lifestyle changes we may need to make to epigenetically improve our own health? Although we are far from [more…]

Natural Compound in Cypress Trees Might Epigenetically Protect Against Cancer

March 21, 2017 Bailey Kirkpatrick

A chemical in an essential oil extracted from tree bark might actually reduce cancer growth. Researchers are finding that hinokitiol, a compound found in some cypress trees, not only has anti-infective and anti-oxidative properties, but it might also impact the epigenetic tags on top of DNA and reactivate genes that fight against tumor growth. The epigenetic mechanism known as DNA methylation has been crucial to our understanding of cancer. Irregular methylation suppresses genes that work to reduce tumor growth, which [more…]

Can Epigenetics Explain the Mystery of Right and Left Handedness?

March 14, 2017 Bailey Kirkpatrick

Are you among the 90% of people who are right-handed or the 10% who are lefties? Have you ever wondered why you naturally favor a certain hand over the other? Now, researchers are suggesting that epigenetics could be the explanation. They are finding that handedness may not be dictated by the brain, as previously thought, but by the environment and epigenetic marks in the spinal cord. “These results fundamentally change our understanding of the cause of hemispheric asymmetries,” the authors concluded [more…]

Air Pollution Could Alter Tags on DNA and Increase Risk for Neurodegenerative Disease

February 21, 2017 Bailey Kirkpatrick

Not only is air pollution a major environmental concern, but it poses major health issues. New research suggests that inhaling extremely small particles known as fine particulate matter could add epigenetic marks to DNA. This may potentially lead to stroke, Alzheimer’s disease, Parkinson’s disease, cognitive impairments and neurodevelopmental disorders. We’re certainly learning more about how our exposure to environmental toxins, especially pollution, affects the chemical tags that attach to our DNA and our health. Previous studies have linked traffic-related air [more…]

What You Eat Adjusts Your Gut Microbiota and Epigenetic Marks

February 14, 2017 Bailey Kirkpatrick

We’ve long known that what we eat affects the microbes in our bodies. Right now, hundreds of different species of bacteria are churning in our stomachs, working to protect us as well as survive within us. New research is showing that the bacterial microbiota of the gut could place chemical tags on our DNA and influence gene expression, potentially impacting our health and many aspects of our lives. Researchers have found that these microbes send out metabolites that impact epigenetic [more…]

Easing Pain with the Power of Epigenetics

February 7, 2017 Bailey Kirkpatrick

Reducing pain effectively is a common goal of modern medicine, and new research suggests that epigenetics might lead us closer to finding out how to ease pain. People who suffer from serious discomfort, such as those who have experienced severe burns, may someday be able to epigenetically ease their pain and reduce neural activation caused by painful stimuli. “Seeking new pain markers continues to be very important in the field of nociception, which analyses the subjective experience of pain, and [more…]

High Estrogen Levels Might Epigenetically Protect Women From a Traumatic Event

January 31, 2017 Bailey Kirkpatrick

Whether a woman’s estrogen level is high or low could determine if she may be susceptible to developing post-traumatic stress disorder (PTSD), according to recent research. Estrogen has been found to epigenetically change gene activity in the brain and could even protect a woman from emotional numbness, flashbacks, and difficulty sleeping – all symptoms of PTSD – after a shocking or traumatic situation. Researchers analyzed an epigenetic mark called DNA methylation, which is known to turn genes off. They used [more…]

High Fat, Low Carb Diet Might Epigenetically Open Up DNA and Improve Mental Ability

January 24, 2017 Bailey Kirkpatrick

Could eating less carbohydrates and more fat relax DNA and boost mental function? Researchers found that a ketogenic diet – consuming high amounts of fat, adequate protein, and low carbohydrates – increases an epigenetic agent naturally produced by the body. This, in turn, may improve memory defects and bolster the growth and development of nervous tissue. In a study published in PNAS, researchers looked at mice with a genetic alteration similar to one found in humans who suffer from a [more…]

Demethylating Agent May Boost Chemotherapy Effectiveness for Specific Type of Childhood Leukemia

January 16, 2017 Natalie Crowley

Fifty years ago, a child diagnosed with acute lymphoblastic leukemia (ALL), the most common type of pediatric cancer, had little to no chance of survival. Today, those odds have increased dramatically thanks to tremendous advances in chemotherapy and other treatments. Cure rates for this type of leukemia can reach as high as 90 percent. Yet, there is one subgroup of pediatric ALL that is still very therapy resistant, T-Acute Lymphoblastic Leukemia (T-ALL). T-ALL is an uncommon, though aggressive, subclass of [more…]

The Epigenetics of Honeybee Memory Offers a Glimpse Into Our Own Minds

January 10, 2017 Bailey Kirkpatrick

The fascinating memory of a honeybee could give us hints about our own long-term memory formation, scientists suggest. According to a new study, epigenetic marks are added to the DNA of honeybees in a response to an enzyme known as DNA methyltransferase (Dmnt) and removed in response to a Dnmt inhibitor drug. This epigenetic mechanism may play a role in memory specificity and influence the removal and re-acquisition of memory. When human memory breaks down or fails, disorders such as [more…]

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