Epigenetics May Provide Relief for Fragile X Syndrome and Intellectual Disorders

November 21, 2017 Tim Barry

Intellectual disabilities affect an individual’s ability to communicate, process information and can severely impact basic life skills of people from all age groups.  Many are a result of a genetic mutation and have often had little insight on any cures or treatments. Recent research published in Cell suggests that epigenetics may play a role in alleviating behavioral symptoms and improving neuronal connections. Fragile X Syndrome is the leading cause for intellectual disability on the genetic level and, until recently, seemed [more…]

The Epigenetic Health Benefits of Blueberries

November 7, 2017 Bailey Kirkpatrick

Although blueberries are tiny, they’re more powerful than you might think. Touted for their high nutrient content – including fiber, vitamin C and K, and manganese – these little blue fruits may be able to adjust chemical marks on DNA and influence our health. Blueberries are incredibly high in antioxidants and it’s thought that this “superfood” can epigenetically reduce DNA damage, thereby protecting humans against aging and cancer. Examples of epigenetics in food include the ability of green tea to [more…]

Epigenetic Drugs That Fight Cancer Also Show Promise as Antivirals

October 31, 2017 Bailey Kirkpatrick

Epigenetic drugs designed to fight cancer might actually be used against many viruses as well. A recent study published in the American Society for Microbiology shows that some pharmaceuticals that act epigenetically have the power to be used as broad spectrum antivirals. Specifically, the researchers looked at histone methyltransferases EZH2/1 inhibitors which can help fight against cancer. Numerous DNA viruses, such as herpes simplex virus (HSV), are involved in epigenetic regulation which determines productive infection, persistence, and latency. Modulation to [more…]

A Glimmer of Hope in the Ugly Face of Addiction: Epigenetics May Help Prevent Relapse

October 24, 2017 Tim Barry

Addiction has become an epidemic that is sweeping not only the nation, but the whole world. Returning substance abusers develop an emotional connection to a situation, environment or people that are present at the time of first usage, which generally means that when they encounter a similar experience, they look to use again. Kicking an addiction and all its symptoms may be one of the hardest things that a human has to endure. Half the battle is stopping use of [more…]

Could Drinking Alcohol Epigenetically Hamper Your Ability to Process Cholesterol?

October 17, 2017 Bailey Kirkpatrick

Scientists from the National Institutes of Health (NIH) and Johns Hopkins Medicine worked together to analyze human and mouse epigenomes and discovered that drinking alcohol could lead to epigenetic changes that influence a particular gene’s ability to regulate cholesterol. The results suggest an underlying epigenetic mechanism known as DNA methylation could explain why someone’s body processes cholesterol differently depending on their drinking habits. It also offers unique insight into the effects of cholesterol-lowering drugs which are commonly used to reduce [more…]

Father’s Exposure to Phthalates Impact Epigenetic Marks on Sperm DNA

October 10, 2017 Bailey Kirkpatrick

New epigenetic research conducted by scientists at the University of Massachusetts suggests that a father’s environment can affect the health of his baby via epigenetic marks in his sperm. Specifically, male exposure to phthalates, which are endocrine disruptors found in plastics, personal care products like shaving cream, and in the environment that surrounds us, were found to have an impact on a couples’ success when having children. Led by Richard Pilsner, an environmental health scientist, this ongoing study supported by [more…]

Exploring the Possibility of Extending Lifespan Using Epigenetic Drift

October 3, 2017 Bailey Kirkpatrick

Nearly a century ago, researchers discovered that cutting calorie intake was actually able to extend lifespan in various animal species. Although numerous studies have been conducted since to find out exactly why reducing calories can extend lifespan, scientists have been unable to pinpoint the answer. Now, a group of investigators at the Lewis Katz School of Medicine at Temple University (LKSOM) have uncovered an explanation to the longevity conundrum, something they call “age-related methylation drift.” The senior investigator, Jean-Pierre Issa, [more…]

Down a Path of Epigenetic Destruction: Smoking Cigarettes Adjusts Critical Marks on DNA

September 26, 2017 Bailey Kirkpatrick

You can now add “harmful changes to your DNA” to the long list of reasons to quit smoking cigarettes, along with lung cancer, coronary heart disease, increased risk of death, stroke, chronic lung disease, decreased immune function, infertility, and the fact that smoking harms nearly every organ in the body. Researchers at the Johns Hopkins Kimmel Cancer Center recently contributed to the growing evidence that demonstrates that smoking cigarettes – which contain a deadly cocktail of over 7,000 chemicals – [more…]

Vitamin D Adjusts Epigenetic Marks That Could Hinder A Baby’s Health

September 12, 2017 Bailey Kirkpatrick

Even though it’s common for expectant mothers to have low vitamin D levels, it’s essential to the health and proper development of the baby. A low amount of vitamin D is associated with poor fetal growth, childhood obesity, bone density, and bone mineral content. Interestingly, key functions of the placenta – like transporting nutrients to the growing baby – are controlled by the expression of genes, which is mediated by vitamin D. Researchers have now discovered that this vitamin might [more…]

An Unlikely Savior: Vinegar Might Epigenetically Protect Plants From Drought

September 5, 2017 Tim Barry

Climate change is undoubtedly one of the greatest threats facing both plants and animals alike. With rising temperatures and irregular weather patterns, droughts have become a far too normal occurrence worldwide. These harsh conditions have proven to be difficult on the survival of agriculture, and scientists all over the world have been searching for a solution to this problem. As genetic engineering becomes more and more developed, scientists have turned to the possibility of editing the genomes of plants to [more…]

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