For The Scientist

The Epigenetics of Chronic Kidney Disease

Chronic kidney disease (CKD) affects 20 million people in the United States and an estimated 8 to 16 percent of…

5 years ago

Scientists Develop a New RNA Sequencing Approach to Advance Our Understanding of the Human Microbiome

The human body is made up of about 100 trillion cells, but not all these cells are ‘real’ human cells.…

5 years ago

Erasure of Tet-Oxidized 5-Methylcytosine by SRAP1

DNA methylation is an essential epigenetic mechanism that plays a critical role in the regulation of gene expression during embryonic…

6 years ago

CRISPR/Cas9-Based Engineering of the Epigenome

It is a challenge to determine a cause and effect relationship between a distinct epigenetic mark and the ultimate behavior…

6 years ago

Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation

Neurogenesis is a highly coordinated process with sequential waves of tightly controlled changes in gene expression. N6-Methyladenosine (m6A), is believed…

6 years ago

An Overview of Single-Cell Epigenomics Methods

Although cells have the same genetic material, they can function differently. Single-cell RNA sequencing has revealed how heterogeneous the transriptome…

6 years ago

A Novel Role for RNA Methylation (m6A) in the DNA Damage Response

Every day our cells undergo substantial amounts of DNA damage from exogenous and endogenous sources. UV light, in particular, can…

7 years ago

Sunshine and Epigenetics: Altering Histone Variant H2A.Z Turnover and Gene Expression in Rice Seedlings

Have you ever thought of how the day-night cycle can epigenetically affect plants? Latest research from Zhang et al. has…

7 years ago

Introducing WERAM: Find Integrated Info on Your Histone Regulator in Your Favorite Species

Recently Dr. Yu Xue’s group, at the Huazhong University of Science and Technology in Wuhan, China, developed a database designated…

7 years ago

The Epigenetic Marks of Circulating Cell-Free DNA (cfDNA)

Circulating cell-free DNA (cfDNA) are small DNA fragments found circulating in plasma or serum, as well as other bodily fluids.…

8 years ago