Articles that explore the connection between epigenetics and diseases and disorders, including cancer, cardiovascular disease, diabetes, autoimmune disease, and more.
A heart attack could leave behind more than just physical damage, according to a new study. Suffering from myocardial infarction, or a heart attack, may lead to the storage of epigenetic marks on certain genes. Researchers from Uppsala University reported in Human Molecular Genetics that an epigenetic “memory” of a heart attack may stick around on DNA long after the heart attack occurred. Both the environment and genetics can determine whether someone is more or less susceptible to cardiovascular disease. [more…]
Eating more plant flavones could reduce your cancer risk, suggests a recent study. By inhibiting epigenetic marks that play a central role in the formation of cancer, some foods may be able to help stave off this widespread disease. According to the American Cancer Society, there will be an estimated 1.6 million new cancer cases in 2016. Interestingly, many foods that are easily accessible have been shown to elicit epigenetic effects that may actually protect against the development of cancer. [more…]
We know that a predisposition to become overweight is found in our genes. Now, we’re starting to learn that epigenetics also has a hand in determining whether a person will become fat or lean. New research is uncovering the possibility of an epigenetic switch that is, interestingly, either “on” or “off”. A group of researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg published their study in Cell. More than one-third of individuals are considered to be [more…]
It’s possible that the impact of traumatic experiences may be epigenetically inherited via molecular memory that is passed down through generations. Although still controversial, new research takes this concept a step further and demonstrates that traumatic behavior could be reversed when it would otherwise be inherited. A study, published in Neuropsychopharmacology, was conducted by researchers at the University of Zurich and ETH Zurich and showed that behavioral symptoms associated with trauma in male mice and their offspring can be undone [more…]
Arthritis is a widespread, debilitating disease characterized by inflammation of the joints. It affects at least 52 million adults in the United States – that’s more than 1 out of every 5 people, according to the CDC. Although medication has improved in recent years, the diversity in pathogenic pathways in certain types of arthritis, for example, rheumatoid arthritis (RA), makes it difficult to pinpoint and alleviate pain in specific joints. Often times, clinical trials for drug treatments focus on alleviating [more…]
Although we typically think the mother has a large impact on her child’s health, epigenetic research is beginning to suggest that a father’s behavior may also have a significant amount of influence. Recently, we posted a blog article on the epigenetic influence a father’s lifestyle has on his children, showing that both mothers and fathers contribute to their offspring’s health through epigenetic alterations. Other research has indicated that a father’s diet could impact his sperm epigenome and influence pregnancy outcomes. [more…]
Could there be connections between socio-economic status, epigenetics, and one’s likelihood of developing depression? Previous and current research has long revealed a relationship between poverty and depression, and now new research suggests that there could be an underlying epigenetic influence. This new finding may help mediate the association between lower socioeconomic status and the risk of developing the disease. The study, published in Molecular Psychiatry, utilizes epigenetics, brain imaging, and behavioral data of adolescents collected over three years as part [more…]
Mothers have often – unfortunately and unfairly – had to carry the burden of being “to blame” for any of their child’s health-related shortcomings. When pregnant women are advised: eat more of this but not too much of that, drink this but definitely none of that… why does dad get off scot-free amid these typically well-intentioned suggestions? Previous studies have, for example, epigenetically linked dad’s drinking to his son’s sensitivity and preference for alcohol and connected a father’s diet to [more…]
We’ve all heard of the risks of the BPA, or Bisphenol A, a chemical used to make durable plastics. BPA can be found in baby bottles, toys, water bottles, and the lining of food cans, but it has also leached into the water and air, travelling around the world. Research has shown this endocrine disruptor can cause adverse health effects during development and impact the reproductive system by mimicking estrogen, binding to nuclear estrogen receptors and even androgen receptors. It [more…]
Diabetes is a disease characterized by the body’s inability to properly use insulin and it affects over 29 million Americans. With new epigenetic research, however, the disease may be mitigated with a simple blood test that offers early knowledge and the possibility for pre-emptive lifestyle management. Lund University researchers in Sweden published their study in Nature Communications, in which they discovered a novel biomarker to predict a person’s risk of developing type 2 diabetes. By using a blood test to [more…]
