Articles that explore the connection between epigenetics and diseases and disorders, including cancer, cardiovascular disease, diabetes, autoimmune disease, and more.

Epigenetically Reactivating a Compromised Immune System with a Specific Sugar

December 13, 2016 Bailey Kirkpatrick

Could a certain type of sugar undo the failure of an individual’s immune system? New research suggests that immune cells can be restored in those with a compromised immune system using a sugar known as beta-glucan, which can turn on an epigenetic “control switch”. For many, getting an infection, such as a sinus infection, feels like an intensified, prolonged cold. Bacterial sinus infections are often easily combated with antibiotics, but typically resolve on their own. However, for more than a [more…]

Binge Drinking as a Teen May Epigenetically Harm the Health of Future Generations

December 6, 2016 Bailey Kirkpatrick

not only harms your brain and body, but may also epigenetically impact your future children, a new study reports. Excessive drinking in adolescents could turn genes on or off in their offspring’s brain, setting them up for susceptibility to certain diseases. The study, presented at the annual Society for Neuroscience meeting on Nov. 14, 2016, suggests that repeated episodes of excessive drinking when you’re young can actually put your future children at risk for developing disorders such as anxiety, depression, [more…]

Eating Sweet, Fatty Foods During Pregnancy is Linked to ADHD in Children

November 22, 2016 Bailey Kirkpatrick

A high-fat, high-sugar diet during pregnancy could be connected to ADHD in children, suggests new research. A mother’s diet may adjust epigenetic marks that attach to her child’s DNA, potentially increasing the odds that he or she will develop ADHD. Attention-deficit/hyperactivity disorder, or ADHD, has become a prevalent condition in modern society as researchers attempt to explain its dramatic rise. As of 2011, around 6.4 million children ages 4 to 17 have been diagnosed with ADHD according to the CDC. [more…]

Smoking Cigarettes Stamps Harmful Epigenetic Fingerprint on DNA

November 8, 2016 Bailey Kirkpatrick

Not only does cigarette smoke severely harm the body, it also leaves behind long-lasting damage on DNA, according to a recent study. An unwanted surplus of chemical marks are added to specific spots on the genome of a smoker, which may give rise to diseases such as a cancer, cardiovascular and lung disorders, and osteoporosis. A group of international researchers conducted a large scale meta-analysis of genome-wide DNA methylation, pulling data from nearly 16,000 people. Around 15% of participants were [more…]

A Heart Attack May Leave Long-Lasting Epigenetic Marks on DNA

October 18, 2016 Bailey Kirkpatrick

A heart attack could leave behind more than just physical damage, according to a new study. Suffering from myocardial infarction, or a heart attack, may lead to the storage of epigenetic marks on certain genes. Researchers from Uppsala University reported in Human Molecular Genetics that an epigenetic “memory” of a heart attack may stick around on DNA long after the heart attack occurred. Both the environment and genetics can determine whether someone is more or less susceptible to cardiovascular disease. [more…]

The Potential Epigenetic and Anticancer Power of Dietary Flavones

October 11, 2016 Bailey Kirkpatrick

Eating more plant flavones could reduce your cancer risk, suggests a recent study. By inhibiting epigenetic marks that play a central role in the formation of cancer, some foods may be able to help stave off this widespread disease. According to the American Cancer Society, there will be an estimated 1.6 million new cancer cases in 2016. Interestingly, many foods that are easily accessible have been shown to elicit epigenetic effects that may actually protect against the development of cancer. [more…]

Epigenetics Could Turn on an ‘Obesity Switch’

September 6, 2016 Bailey Kirkpatrick

We know that a predisposition to become overweight is found in our genes. Now, we’re starting to learn that epigenetics also has a hand in determining whether a person will become fat or lean. New research is uncovering the possibility of an epigenetic switch that is, interestingly, either “on” or “off”. A group of researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg published their study in Cell. More than one-third of individuals are considered to be [more…]

Inherited Epigenetic and Behavioral Consequences of Trauma Could be Reversed

August 16, 2016 Bailey Kirkpatrick

It’s possible that the impact of traumatic experiences may be epigenetically inherited via molecular memory that is passed down through generations. Although still controversial, new research takes this concept a step further and demonstrates that traumatic behavior could be reversed when it would otherwise be inherited. A study, published in Neuropsychopharmacology, was conducted by researchers at the University of Zurich and ETH Zurich and showed that behavioral symptoms associated with trauma in male mice and their offspring can be undone [more…]

Arthritic Joints May Need Different Treatments Due to Diverse Epigenetic Signatures

July 19, 2016 Bailey Kirkpatrick

Arthritis is a widespread, debilitating disease characterized by inflammation of the joints. It affects at least 52 million adults in the United States – that’s more than 1 out of every 5 people, according to the CDC. Although medication has improved in recent years, the diversity in pathogenic pathways in certain types of arthritis, for example, rheumatoid arthritis (RA), makes it difficult to pinpoint and alleviate pain in specific joints. Often times, clinical trials for drug treatments focus on alleviating [more…]

Overweight Fathers May Epigenetically Increase Their Daughters’ Risk of Breast Cancer

July 5, 2016 Bailey Kirkpatrick

Although we typically think the mother has a large impact on her child’s health, epigenetic research is beginning to suggest that a father’s behavior may also have a significant amount of influence. Recently, we posted a blog article on the epigenetic influence a father’s lifestyle has on his children, showing that both mothers and fathers contribute to their offspring’s health through epigenetic alterations. Other research has indicated that a father’s diet could impact his sperm epigenome and influence pregnancy outcomes. [more…]

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