Articles that explore the connection between epigenetics and diseases and disorders, including cancer, cardiovascular disease, diabetes, autoimmune disease, and more.

Fathers Affected by Early Life Trauma May Impact Later Generations Through Sperm MicroRNAs

June 5, 2018 Tim Barry

When it comes to reproductive health, it’s no secret that a pregnant mother’s choices and environment can severely impact her child’s epigenetics and health—especially mothers suffering from PTSD. But it turns out fathers who have suffered significant stress early on in their life may also epigenetically impact the physical and mental health of their offspring. It was previously thought that fathers only passed DNA to the mother’s egg during fertilization, but it was recently discovered that sperm also contributes miRNA, [more…]

Toxins May Affect Epigenetics Through Multiple Generations

May 21, 2018 James Cain

Organic foods are rather popular in shopping baskets nowadays. After all, avoiding those pesky pesticides that are used on a vast amount of produce is surely good for our health. But what about the health of our children and their children thereafter? We already know that the life experiences of our mothers and fathers can influence the epigenetics in their children. Epigenetics may also be ‘remembered’ through the phenomena known as transgenerational inheritance; so the pesticides your great-granddad may have [more…]

Epigenetics, Nutrition, and Our Health: How What We Eat Could Affect Tags on Our DNA

May 15, 2018 Bailey Kirkpatrick

Many of us are familiar with the foods that damage our bodies – they slow our metabolism, might add a few pounds, and stiffen our arteries. But what if certain food items could help or harm us in a place we may never have considered – like our DNA? A developing field called nutriepigenomics examines the connection between diet and chemical marks that can be attached to or removed from our DNA, thereby turning genes on or off. Many new [more…]

Epigenetic Study Identifies a Novel Biomarker for an Elusive Bladder Disease

May 8, 2018 Natalie Crowley

Running to the restroom is normal when you’ve got a full bladder ready to burst. But constantly feeling the urge to go multiple times a day can be uncomfortable and debilitating, especially if it’s accompanied by severe pelvic pain. For those suffering from interstitial cystitis (also called painful bladder syndrome), this is an unfortunate reality – one that is often misdiagnosed and challenging to treat. In a recent study published in Scientific Reports, researchers from the US and Korea may [more…]

Epigenetics Clues to Obesity and How Lifestyle Changes Could Modify Your Epigenetic Profile

May 1, 2018 Estephany Ferrufino

Adiposity is a condition of being severely overweight or obese and it has numerous connections to epigenetics. Understanding more about the epigenetics underlying obesity could help to introduce preventions based on lifestyle changes which may be able to modify our epigenetic marks and improve health. A rough measure of obesity is body mass index, BMI, which can be calculated by dividing one’s body weight in kilogram by the body height in square meters. According to the World Health Organization (WHO) [more…]

Early Epigenetic Nutrition ‘Memory’ Could Program You for Obesity Later in Life

April 24, 2018 Bailey Kirkpatrick

For decades, we’ve known how important it is to receive proper nutrition during early stages of life. Nutritional experiences in the beginning of development can set the stage for many things, including body weight, and can even affect the risk of obesity as we get older. Recent research supports the idea that poor nutrition at the beginning of pregnancy or while a baby is nursing can be stored as molecular epigenetic “memory” on the child’s genome, potentially setting them up [more…]

Protective Epigenetic Marks Go Awry in Alzheimer’s Disease

April 10, 2018 Tim Barry

Alzheimer’s disease (AD) is a complex neurodegenerative disease that occurs due to an accumulation of amyloid plaques and neurofibrillary tangles in the brain. It affects over 5 million Americans of all ages, particularly those over 65 years of age and is one of the leading causes of death in the US. Currently, there are no sure ways to cure, prevent or even slow down progression of the disease. It is believed to be caused by a combination of genetic and [more…]

Researchers Combine Epigenetics and Brain Imaging to Help Combat PTSD

April 3, 2018 Estephany Ferrufino

Post-traumatic stress disorder (PTSD) is a mental health issue that some people develop after experiencing or witnessing a life-threatening or intensely stressful event. PTSD can exert an enormous toll on an individual’s life, affecting their daily activities and relationships. According to the National Center for PTSD, about 7 or 8 of every 100 people will experience this disorder at some point in their lives. Anyone can develop PTSD at any age, including children, war veterans, and people who have been [more…]

Epigenetics May Explain Why Stress From Exercise is Good for the Heart

March 6, 2018 Tim Barry

In the exercise community, it is often preached that working out is a form of medicine and can be crucial to maintaining a healthy lifestyle. Routine exercise helps to retain healthy body weight and has been shown to lower the risk of diseases such as diabetes, obesity, and high blood pressure. It’s even been shown to keep the brain healthy. High-intensity exercise places a “good stress” on the heart allowing robust function – but why is stress from exercise considered [more…]

Paternal Environmental and Lifestyle Factors Influence Epigenetic Inheritance

February 28, 2018 Estephany Ferrufino

There is strong evidence that suggests certain environmental or lifestyle factors may lead to increased risk of developing chronic diseases. These factors such as diet, behavior, stress, exposure to pollutants, and physical activity have been known to cause epigenetic changes which may be passed down from one generation to the next. It is believed that a father’s exposure to environmental factors can play a role in an offspring’s epigenetic patterns and health. Recent evidence suggests that sperm epigenetic modifications can [more…]

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