Epigenetic Changes Due to Aging May Lead to Cancer

August 21, 2018 Tim Barry

Throughout our lives, all cells in our bodies experience a normal life cycle of growth, maturity, and death. During this time, our cells normally experience damage to DNA by normal functions of the metabolism, or exposure to certain environmental factors like UV light. Ordinarily, our body is able to repair the damage done to the DNA in order to restore healthy cell function. The older we get, the more DNA damage we experience, and if damaged DNA is unable to [more…]

Exploring the Possibility of Extending Lifespan Using Epigenetic Drift

October 3, 2017 Bailey Kirkpatrick

Nearly a century ago, researchers discovered that cutting calorie intake was actually able to extend lifespan in various animal species. Although numerous studies have been conducted since to find out exactly why reducing calories can extend lifespan, scientists have been unable to pinpoint the answer. Now, a group of investigators at the Lewis Katz School of Medicine at Temple University (LKSOM) have uncovered an explanation to the longevity conundrum, something they call “age-related methylation drift.” The senior investigator, Jean-Pierre Issa, [more…]

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