…and viruses that live within us and on us. These organisms are collectively known as microbes and they play an essential role in human health and disease. Yet, exactly how…
…withdrawal symptoms, and the desire to use again. Previously, it had been studied that an epigenetic drug could alter DNA methylation in the brain during drug withdrawal with hopes in…
…both spring and autumn. The researchers looked at particulate matter of various sizes (PM2.5 and PM10) and nitrogen dioxide (NO2), and measured these air pollutants once every hour. In order…
…methylation potential is disrupted. m6A methylation regulates the nuclear processing of mRNA. Circadian clock genes have multiple m6A methylation sites. Therefore, lack of m6A-RNA methylation causes a delay in RNA…
…and gene expression has been widely recognized. DNA hypomethylation is likely caused by methyl-deficiency due to a variety of environmental influences and has been proposed as a molecular marker in…
…a delay in cell-cycle progression and the m6A methylation plays a role in cortical neurogenesis. In order to confirm that the phenotypes observed were due to m6A and not to…
…Paulo looked at DNA methylation patterns in obese women versus women with BMI in the normal range, and how these patterns could affect health outcomes. DNA methylation is an epigenetic…
…used to detect diseases like pancreatic cancer and type 2 diabetes. The team performed genome-wide DNA methylation analysis of the thyroid, heart, and brain from 10 cadavers. They were then…
…from the retinal pigment epithelium (RPE) of 44 human eyes: 25 AMD and 19 control. They performed genome-wide methylation analysis to measure DNA methylation levels in the genes associated with…
…Advanced age has been known to cause disruptions in DNA methylation in sperm, including the specific genes that correlate with ASD. DNA methylation abnormalities in the male gamete associate with…
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