…of histones and DNA – ultimately reducing cancer cell viability via a cell cycle arrest. The researchers suggest that DNA methylation, another popular epigenetic mechanism, should be investigated in terms…
…as we age. Research over the past few years has shown that aging is a process that involves epigenetic factors, like changes in DNA methylation, post-translational modifications of histones, and…
…like histone modification, DNA methylation, small non-coding RNAs and chromatin architecture. And, these epigenetic mechanisms regulate nearly all biological processes from conception to death, including genome reprogramming and cell differentiation…
…a DNA methyltransferase inhibitor that removes methyl groups from DNA, and the other with histone deacetylase inhibitors (HDACi), an epigenetic enzyme that allows DNA to uncoil from histones. They then…
…of research has aimed to unravel the connection between epigenetic modifications and the emergence of autoimmune disorders. Epigenetic mechanisms, including DNA methylation, histone modifications, and noncoding RNAs, primarily control gene…
…and methyltransferase-like 14 (Mettl14) as the SAM-binding sub-unit. The role of m6A modification in cancer has previously been investigated. Now, the Yoon et al. (2017) study demonstrates that m6A methylation…
…without obstacles. DNA is tightly packaged in a complex called chromatin, making it difficult for transcriptional access. It can be vulnerable to histone methylation, an epigenetic mechanism that can affect…
Post-translational modifications are well known for their influence on protein stability, enzymatic functions, as well as protein:protein interactions. At the level of gene expression, acetylation, methylation, phosphorylation, ADP-ribosylation, ubiquitination and…
…and growth of plants by causing DNA damage. Therefore, an efficient DNA damage response is crucial to ensure optimum growth and survival of plants. Our study reveals one possible epigenetic…
Could eating less carbohydrates and more fat relax DNA and boost mental function? Researchers found that a ketogenic diet – consuming high amounts of fat, adequate protein, and low carbohydrates…
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