About Sadman Sakib
M. Sadman Sakib, originally from Bangladesh, finished his master’s degree in Neuroscience jointly from University of Goettingen, Germany and University of Bordeaux, France. Although he obtained his bachelor degree in biochemistry & molecular biology at University of Dhaka, Bangladesh, currently he is pursuing his PhD studies in international Max Planck research school for neurosciences in Goettingen, Germany. His current research foci range from epigenetics towards aging, environmental enrichment and neurodegeneration. When he is out of the lab, he enjoys travelling and cooking.

Bisphenol A Can Reprogram Liver’s Epigenome and Result in Disease in Rats

July 7, 2020 Sadman Sakib

There has been growing literature that suggests how environmental chemical exposure can lead to birth defects but the majority of the studies are association based. A fraction of those studies have shown how ambient chemical exposure affects insulin sensitivity and lipid metabolism1  or affecting gut-microbiota2. But how early life chemical exposure can affect epigenetics—or change the epigenome and drive the effect till later life was missing. A new study published recently in Nature Communication by Dr. Lindsey Treviño and her [more…]

Sunshine and Epigenetics: Altering Histone Variant H2A.Z Turnover and Gene Expression in Rice Seedlings

March 7, 2017 Sadman Sakib

Have you ever thought of how the day-night cycle can epigenetically affect plants? Latest research from Zhang et al. has shown a possible mechanism of how histone variants can negatively regulate gene expression in day-night cycles of rice seedling tissues. This paves a way for an exciting area of research of how histone variants can be differentially deposited in a very short time span, in order to fine tune the transcription due to the environmental stimuli in plants. Histones variants, [more…]

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