New Method Simultaneously Profiles Methylome and Transcriptome in the Same Single Cell
A new single-cell genomics protocol that is potentially transformative for epigenetics research has been developed by scientists in the UK and Belgium. Applying this method, it is now possible to study the epigenome and transcriptome of a single cell at the same time. This novel approach could enhance our understanding of the link between gene expression and DNA methylation in single cells. Also, the knowledge of this relationship may clarify the mechanisms underlying normal development, and changes that occur with [more…]