DNA Methylation Editing: Expert Insights into the Technologies, Challenges, and Future Perspectives

December 26, 2023 Mike Spelios

This article was first published by¬†EpigenTek. Since the 1970s when studies on the epigenetics of chromatin first started, histone and DNA marks, especially DNA methylation, have become the most investigated and characterized epigenetic modifications to date [Razin]. DNA methylation has garnered significant attention within the field as a pivotal regulator of gene expression. Its extensive influence on biological processes, ranging from development to disease, has redefined our comprehension of genetic control and prompted innovative approaches for medical interventions. During development, [more…]

Twins Study Reveals Epigenetic Signature Linked to Obesity

December 12, 2023 Elizabeth Fontanilles

Obesity stands as a multifaceted health concern affecting millions worldwide. While diet and lifestyle play pivotal roles, researchers are now looking much deeper to determine if susceptibility to obesity could be identified at a molecular level within human cells. In a recent study led by distinguished biology professor Michael Skinner at Washington State University (WSU), a comprehensive twin study was undertaken to probe the epigenetic factors associated with obesity. Their findings uncovered specific DNA methylation regions (DMRs) intricately connected to [more…]

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