January 2023 | What is Epigenetics?

Epigenetic Switch Helps the Body Fight Infections

January 31, 2023 Natalie Crowley

Keeping the body healthy – that’s the immune system’s job. And a healthy immune system allows our body to defend against invading disease-causing microorganisms like viruses, parasites, and bacteria. One remarkable component of the immune system response is hematopoiesis, the process by which immune cells are produced in the bone marrow. During an infection, the hematopoietic system kicks into high gear, replenishing the immune cells that are quickly being consumed. Like a “state of emergency” for the body, this system [more…]

The Benefits of Exercise Goes Epigenome-Deep

January 17, 2023 Natalie Crowley

Not everyone likes to exercise, but let’s face it, exercise is essential for good health. In addition to keeping weight in check, it helps combat many physical and mental disorders. Numerous studies have attested to the benefits of exercise, providing data supporting its role in preventing and managing conditions like heart disease, diabetes, cancer, depression, and anxiety. So then, why isn’t exercise something we all do regularly? Some say we live in an “obesogenic” world, where inactivity is more or [more…]

Histone mimicry: How a SARS-CoV-2 protein functions as an H3 mimic to disrupt host cell epigenetic regulation

January 3, 2023 Mike Spelios

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first recognized at the beginning of 2020 and is responsible for the ongoing COVID-19 pandemic. The persistence of the virus has been partly accredited to its effective suppression of host cell responses. As such, continued research in elucidating the dynamics of the SARS-CoV-2 life cycle is essential to facilitate the design and development of novel diagnostics and suitable therapies. Although reports suggest that SARS-CoV-2 can dysregulate the host’s gene expression and innate [more…]

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