Predicting Schizophrenia Risk Based on Epigenetics

August 31, 2021 Natalie Crowley

Schizophrenia is a complex and severe mental illness that affects approximately 1% of the global population. Often misdiagnosed for symptoms similar to other cognitive disorders, this condition lacks a valid biochemical laboratory test to support its clinical diagnosis. Studies have shown that schizophrenia has both genetic and environmental components, suggesting that epigenetic dysregulation is likely an important contributor to its etiology. Thus, developing a diagnostic tool that can identify these abnormal epigenetic modifications could help detect the disease properly and [more…]

A Stimulating Environment May Prevent The Brain From Epigenetically Aging

August 17, 2021 Natalie Crowley

One unfortunate side effect of aging is loss of brain function. For most people, it starts off here and there with some “forgetfulness” or a modest decline in other thinking skills. But brain loss can be progressive as we age and lead to more problematic conditions such as dementia or Alzheimer’s. One possible key to maintaining brain functioning and staying sharp-minded could be as simple as living a varied and active life. While this notion isn’t new, current research is [more…]

Epigenetic Alteration Linked To Lung Cancer Relapse

August 3, 2021 Natalie Crowley

Chemotherapy has been the mainstay for lung cancer treatment for decades. Unfortunately, even after an initial positive response to it, tumors can sometimes develop drug resistance. When this happens, there is little doctors can do to improve a patient’s outcome, as the survival rate after relapse can be devastatingly low. Understanding exactly what causes this cancer to rebound has scientists taking a closer look at the genetic diversity of lung tumors, in particular their epigenetic signature. In recent years, genomic [more…]

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