What is Paleoepigenetics?

April 30, 2019 Hayley Mann

To unravel the complexities surrounding the genome, advanced technologies in genomics and epigenetics are typically necessary. Most of these tests and instruments are designed with high-quality DNA and tissue specimens in mind. Accordingly, scientists preferentially use concentrated and freshly extracted DNA to achieve the best results. Yet, some researchers do not have the luxury of working with modern DNA. This is why the field of ancient DNA (aDNA) emerged. Evolutionary biologists and anthropologists that study humans and other organisms from [more…]

Neurotransmitter Serotonin is Welcomed as a Potentially New Epigenetic Mark

April 23, 2019 James Cain

The neurotransmitter serotonin (also known as 5-hydroxytryptamine (5-HT)) has an absolute vast array of functions across the human body. Most commonly known to regulate mood, it is also key for the development of neurones. In fact, serotonin is linked to various mental disorders, including depression, which globally affects more than 300 million people. It has long been assumed that serotonin has an indirect role in relation to epigenetic regulation1. The binding of serotonin to its receptor(s) causes a downstream cascade [more…]

Epigenetics Involved in Improving COPD Treatment

April 16, 2019 Natalie Crowley

Breathing can be difficult for millions of people around the world who have COPD. While there are available treatments that can reduce the symptoms of this condition, one major barrier to their effectiveness is corticosteroid resistance. The mechanisms that contribute to this type of resistance are unknown, but recent evidence suggests that certain epigenetic factors may play a role. COPD (or chronic obstructive pulmonary disease) is a term used to describe progressive lung diseases including chronic bronchitis and emphysema. Long-term [more…]

Teen Drinking Could Epigenetically Hinder Brain Development

April 9, 2019 Tim Barry

Alcohol is likely the most used and abused substance in the world. It’s fine to have a few cocktails or beers per week, but only for those that are of the legal drinking age. Underage drinking is a consistent issue faced in the United States today. According to the CDC, kids ages 12-20 consume about 11% of all alcohol in the US, and this can be problematic as it is often done in a bingeing manner, rather than a causal [more…]

Seed Dormancy Stems from the Mother Plant Via Epigenetics

April 2, 2019 Natalie Crowley

The seed stage is an integral part of a plant’s life cycle and necessary for species’ survival. As the dispersal unit of the organism, the seed must be able to sustain extended periods of unfavorable conditions if necessary. It does this by remaining dormant, thereby delaying germination until the environment is ideal. Biologists at the University of Geneva (UNIGE), Switzerland previously revealed that seed dormancy is inherited from the mother plant. Now, this same team has uncovered how this maternal [more…]

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