Epigenetic Marks on a Stress-Related Gene Linked to Suicide Risk

December 26, 2017 Bailey Kirkpatrick

Many people consider suicide to be taboo, and it’s a subject that is often avoided. However, the more we understand the reasoning behind why some people are pressed to commit suicide, the better equipped we may be to offer support and guidance for treatment. Interestingly, certain lifestyles and various environmental factors might be able to influence a specific gene linked to stress, which could increase suicide risk in adults and even adolescents. In a new study, researchers from Uppsala University, [more…]

Panic Disorder Might Have an Epigenetic Explanation

December 18, 2017 Estephany Ferrufino

Fight-or-flight is a physiological response that occurs when an individual has been exposed to a perceived threat. This well-known stress response pathway is critical for the survival of many organisms. However, people with different types of anxiety-driven disorders can experience intense stress even with little to no stimuli. For individuals who suffer from anxiety disorders, the feeling of worry and anxiety do not go away. The recurring waves of fear that set off a fight-or-flight response may interfere with daily [more…]

Cuddling Can Leave Positive Epigenetic Traces on Your Baby’s DNA

December 12, 2017 Bailey Kirkpatrick

You might be familiar with the popular epigenetic study that suggests when mother rats lick their pups, they leave epigenetic marks on their babies’ DNA. This, in turn, helps them grow up to be calm adults. On the other hand, pups who receive very little licking, grooming, or nursing from their moms tend to grow up more anxious. It wasn’t their genes that dictated their stressed-out behavior, but their epigenome, which was shaped by the nurturing behavior of their mother [more…]

An Overview of Single-Cell Epigenomics Methods

December 7, 2017 Estephany Ferrufino

Although cells have the same genetic material, they can function differently. Single-cell RNA sequencing has revealed how heterogeneous the transriptome of an individual cell may be with a homogeneous cell population or tissue.  Single-cell genome sequencing has provided insights into genomic variations that occur in physiology and in diseases. Today we can probe the majority of epigenetic dimensions with single-cell resolution through multiple methods (Table 1). Studying individual cells offers insight into molecular components of the genome and its functional [more…]

Skipping Sleep Lowers the Body’s Protective Antioxidant Levels and Induces Epigenetic Changes

December 5, 2017 Natalie Crowley

Sleep is something that nearly all species need to survive. On a daily basis, humans need about 8 hours, dogs and cats recharge with around 12 hours, and the koala takes nearly the entire day — napping a whopping 22 hours. But unlike dogs, koalas, or most other animals, we humans don’t always get enough of our required Zzz’s. Our lives are either too busy or filled with too many distractions that keep us up at night. Sometimes sleep is [more…]

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