For The Scientist

Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis Revealed by High-Resolution Mapping

In eukaryotic RNA, the methylation of adenosine at the N6 position to form N6-methyladenosine (m6A) is the most common and…

12 years ago

Transposase-Accessible Chromatin Assay for Fast and Sensitive Epigenomic Profiling

Scientists at Stanford University School of Medicine have developed a rapid and sensitive method for integrative epigenomic analysis called assay…

12 years ago

New Technique Available to Measure m6A Levels for RNA Methylation Studies

Researchers at Epigentek recently developed a new and breakthrough approach to identify the "fifth base" of RNA, N6-methyladenosine (m6A) to…

12 years ago

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

The scientists at MIT describe an approach for efficient targeted demethylation of specific CpGs in human cells using fusions of…

12 years ago

DNMT1-Interacting RNAs Block Gene-Specific DNA Methylation

5-methylcytosine is found in the context of paired symmetrical methylation of a CpG site. In normal somatic cells, most CpG…

12 years ago

A New Study Shows MicroRNA-26a Targets DNA Demethylation Enzymes

In their studies, the scientists at Beckman Research Institute of City of Hope demonstrated that Ten eleven translocation (TET) enzymes…

12 years ago

“Post-Bisulfite” and Higher Sensitivity DNA Library Preparation Technology for Epigenetics-Targeted Next Generation Sequencing Analysis

Scientists at Epigentek developed a series of new products for DNA library preparation used in next generation sequencing analysis of…

12 years ago

Novel Assay to Probe the DNA Methylation State of Multiple Genomic Loci in Single Cells

The scientists from A*STAR's Institute of Medical Biology (IMB) and Institute of Molecular and Cell Biology (IMCB)  developed a novel…

12 years ago

Chromatin Remodelers Fine-Tune H3K36me-Directed Deacetylation of Neighbor Nucleosomes by Rpd3S

To form chromatin, DNA is tightly wrapped around nuclear proteins called histones. The repeating DNA-histone complex, which consists of 146…

12 years ago

Epigenetic Memory at Embryonic Enhancers Identified in DNA Maps from Adult Mouse Tissues

In human DNA, 5-methylcytosine is found in approximately 1.5% of genomic DNA. In somatic cells, 5-mC occurs almost exclusively in…

12 years ago