For The Scientist

m6A Editing: Harnessing CRISPR-Cas for Programmable RNA Modification

“The fifth RNA base” N6-methyladenosine, or m6A, is the most common and abundant eukaryotic RNA modification, accounting for over 80%…

3 years ago

Accessing Histone PTMs: Insights Into the Methods Used for Their Assessment

This article was first published by EpigenTek. In the early 1960s, Vincent G. Allfrey and his colleagues at the Rockefeller…

3 years ago

The Epigenetics of Antifungal Resistance

Decades of antibiotic and antifungal use have dramatically impacted the global microbiome, with ramifications for agriculture and human health. Worries…

3 years ago

3D-Imaging for Epigenetic Changes in the Brain 

For centuries, scientists and philosophers have been fascinated with learning about the brain. However, it hasn’t been until the last…

4 years ago

A Role for m6A Methylation in the Immune Response of Natural Killer Cells Toward Cancer

The body’s first line of defense against infection is the innate immune system. Although it is non-specific and less effective…

4 years ago

Breakthrough Technique Calculates Gene Regulation at the Single-Cell Level Using Deep-Learning

A new technique has been developed that is expected to advance our knowledge of numerous underlying biological processes, including those…

5 years ago

Histone Modifications – Regulators of Viral Infection

Histones are the most eminent DNA-interacting proteins.  As the primary protein constituent of chromatin, forming complexes with DNA to compact…

5 years ago

The Epigenome of Circulating Cell-Free DNA as a Biomarker of Disease

Cells are continually being generated and eliminated by our bodies in an ongoing cycle crucial for maintaining proper tissue structure…

6 years ago

How to Choose an Antibody: For Beginners

Antibodies are used extensively in research for procedures, such as western blotting (WB), enzyme-linked immunosorbent assays (ELISA), and immunoprecipitation (IP).…

6 years ago

DNA Deaminase-Based Hydroxymethyl–Seq: Nondestructive and Base-Resolution

The most common epigenetic mark throughout the genome is 5-methylcytosine (5mC). Additionally, 5-hydroxymethylcytosine (5hmC) is also known to play a…

6 years ago