Aging is a normal process linked to specific patterns and changes in the epigenome, particularly DNA methylation. Harnessing epigenetic mechanisms and understanding the epigenetic clock might enable us to slow or reduce human aging in the future, especially as scientific research reveals new associations and insights.

After DNA methylation patterns have been established during embryogenesis, researchers investigate how they are maintained, and how the environment can influence changes to marks on top of DNA during one’s lifespan.

EpigenCare Pioneers Personalized Skincare Based on Your Unique Epigenetic Signature

March 15, 2018 Bailey Kirkpatrick

Pinpointing factors that make a person unique could shift the entire landscape of how we attend to our health – from exercise plans to custom diets and even skincare regimens. The concept of personalization has pierced the bubble of the prevailing “one size fits all” mentality, deflating the flawed notion that what works for the majority will likely work for anyone. When it comes to our bodies’ largest organ, and caring for it effectively, epigenetics may provide an answer. Our [more…]

Maybe She’s Born With it, Maybe it’s Epigenetics: 5 Tips for Beauty and Anti-Aging

February 20, 2018 Bailey Kirkpatrick

We might say a beautiful woman is born with her looks or that she was endowed with good genes. But what if some of her beauty comes from reversible marks on top of her genes? The epigenetic tags on her DNA might be contributing to her glowing skin, young complexion, and silken hair. Interestingly, there may even be ways in which simple lifestyle changes could adjust these epigenetic tags, modulating the expression of certain genes that promote beauty and health. [more…]

Exploring the Possibility of Extending Lifespan Using Epigenetic Drift

October 3, 2017 Bailey Kirkpatrick

Nearly a century ago, researchers discovered that cutting calorie intake was actually able to extend lifespan in various animal species. Although numerous studies have been conducted since to find out exactly why reducing calories can extend lifespan, scientists have been unable to pinpoint the answer. Now, a group of investigators at the Lewis Katz School of Medicine at Temple University (LKSOM) have uncovered an explanation to the longevity conundrum, something they call “age-related methylation drift.” The senior investigator, Jean-Pierre Issa, [more…]

Epigenetic Enzyme Could Play a Role in Reducing Fat as We Age

May 16, 2017 Bailey Kirkpatrick

Whether we like it or not, we’re faced with many physical changes as we get older. Wrinkles form, bones and muscles grow weaker… even the way fat is distributed throughout the body changes radically. As we age, we lose a certain type of fat cell that burns fatty deposits, which increases the risk for obesity. But there may be hope. Interestingly, researchers are finding that an epigenetic enzyme might be able to prevent this pesky change from happening. Epigenetics has [more…]

Epigenetic Clock Destines Some to Age Faster Regardless of Lifestyle

November 1, 2016 Bailey Kirkpatrick

Certain people will age quicker and die sooner, even if they keep their body healthy, suggests a largescale analysis by UCLA scientists. Regardless of how well you take care of yourself, an accelerated internal epigenetic clock may lead to an earlier death for some. Researchers assessed data from over 13,000 individuals, measuring levels of DNA methylation in hundreds of specific areas on the genome to determine their “epigenetic age.” Epigenetic marks found on DNA and histone proteins are known to [more…]

Certain Ethnic Groups May Epigenetically Age Slower

October 4, 2016 Bailey Kirkpatrick

Scientists have been curious about whether race or ethnicity directly impact molecular markers of aging. Could people of certain race be more likely to age faster or slower? A group of researchers from UCLA conducted a study that was the first of its kind, demonstrating that Latinos actually age more slowly than other ethnic groups. On average, Latinos live three years longer than Caucasians. Even though Latinos are shown to have longer lives, they actually experience a greater rate of [more…]

Can Your Age Influence the Epigenetic Effects of Exercise?

September 27, 2016 Bailey Kirkpatrick

We all know the extensive benefits of exercise: work out to stave off disease, improve mental acuity, lose weight, reduce stress, and so on. But even with all these benefits, there are still some questions surrounding the molecular causes that underlie them. Epigenetics has been particularly helpful in gaining new insights into the wide range of health benefits of exercise. Recently, a study showed that exercise could epigenetically keep the brain healthy by boosting the production of a protein called [more…]

Menopause and Insomnia Might Epigenetically Speed Up Aging

September 13, 2016 Bailey Kirkpatrick

For years, scientists have disagreed on whether menopause causes aging or aging leads to menopause, giving rise to a “which came first” debate. New epigenetic research may help settle this long-standing disagreement, offering evidence that menopause might actually make a woman age faster. Two recent UCLA studies show that menopause and its common side effect – insomnia – may accelerate aging. This could potentially increase a woman’s risk for diseases related to aging and possibly lead to an earlier death. [more…]

Arthritic Joints May Need Different Treatments Due to Diverse Epigenetic Signatures

July 19, 2016 Bailey Kirkpatrick

Arthritis is a widespread, debilitating disease characterized by inflammation of the joints. It affects at least 52 million adults in the United States – that’s more than 1 out of every 5 people, according to the CDC. Although medication has improved in recent years, the diversity in pathogenic pathways in certain types of arthritis, for example, rheumatoid arthritis (RA), makes it difficult to pinpoint and alleviate pain in specific joints. Often times, clinical trials for drug treatments focus on alleviating [more…]

Could Epigenetics Rescue Cognitive Impairment Caused by Getting Old?

May 10, 2016 Bailey Kirkpatrick

As we get older, our cognitive ability declines, especially our memory. Although aging-related cognitive impairment occurs naturally, humans have been fascinated since ancient times with uncovering a “fountain of youth” to ensure that our beauty, minds, and youthful qualities stay with us forever. What if we could stave off or protect our brain function as we age? With new research in epigenetics, we may be closer to finding out what’s behind memory loss and cognitive impairment. A study published in [more…]

1 2