Articles that explore the connection between epigenetics and diseases and disorders, including cancer, cardiovascular disease, diabetes, autoimmune disease, and more.

Inherited Epigenetic and Behavioral Consequences of Trauma Could be Reversed

August 16, 2016 Bailey Kirkpatrick

It’s possible that the impact of traumatic experiences may be epigenetically inherited via molecular memory that is passed down through generations. Although still controversial, new research takes this concept a step further and demonstrates that traumatic behavior could be reversed when it would otherwise be inherited. A study, published in Neuropsychopharmacology, was conducted by researchers at the University of Zurich and ETH Zurich and showed that behavioral symptoms associated with trauma in male mice and their offspring can be undone [more…]

Arthritic Joints May Need Different Treatments Due to Diverse Epigenetic Signatures

July 19, 2016 Bailey Kirkpatrick

Arthritis is a widespread, debilitating disease characterized by inflammation of the joints. It affects at least 52 million adults in the United States – that’s more than 1 out of every 5 people, according to the CDC. Although medication has improved in recent years, the diversity in pathogenic pathways in certain types of arthritis, for example, rheumatoid arthritis (RA), makes it difficult to pinpoint and alleviate pain in specific joints. Often times, clinical trials for drug treatments focus on alleviating [more…]

Overweight Fathers May Epigenetically Increase Their Daughters’ Risk of Breast Cancer

July 5, 2016 Bailey Kirkpatrick

Although we typically think the mother has a large impact on her child’s health, epigenetic research is beginning to suggest that a father’s behavior may also have a significant amount of influence. Recently, we posted a blog article on the epigenetic influence a father’s lifestyle has on his children, showing that both mothers and fathers contribute to their offspring’s health through epigenetic alterations. Other research has indicated that a father’s diet could impact his sperm epigenome and influence pregnancy outcomes. [more…]

Poor Socioeconomic Status May Leave Epigenetic Mark on Gene Linked to Depression

June 7, 2016 Bailey Kirkpatrick

Could there be connections between socio-economic status, epigenetics, and one’s likelihood of developing depression? Previous and current research has long revealed a relationship between poverty and depression, and now new research suggests that there could be an underlying epigenetic influence. This new finding may help mediate the association between lower socioeconomic status and the risk of developing the disease. The study, published in Molecular Psychiatry, utilizes epigenetics, brain imaging, and behavioral data of adolescents collected over three years as part [more…]

Dad’s Life Experiences May Epigenetically Influence His Children’s Health

May 31, 2016 Bailey Kirkpatrick

Mothers have often – unfortunately and unfairly – had to carry the burden of being “to blame” for any of their child’s health-related shortcomings. When pregnant women are advised: eat more of this but not too much of that, drink this but definitely none of that… why does dad get off scot-free amid these typically well-intentioned suggestions? Previous studies have, for example, epigenetically linked dad’s drinking to his son’s sensitivity and preference for alcohol and connected a father’s diet to [more…]

Could Common Chemicals Tip the Epigenetic Balance and Program Someone for Obesity?

May 24, 2016 Bailey Kirkpatrick

We’ve all heard of the risks of the BPA, or Bisphenol A, a chemical used to make durable plastics. BPA can be found in baby bottles, toys, water bottles, and the lining of food cans, but it has also leached into the water and air, travelling around the world. Research has shown this endocrine disruptor can cause adverse health effects during development and impact the reproductive system by mimicking estrogen, binding to nuclear estrogen receptors and even androgen receptors. It [more…]

Could a New Epigenetic Blood Test Predict Your Risk of Type 2 Diabetes?

May 17, 2016 Bailey Kirkpatrick

Diabetes is a disease characterized by the body’s inability to properly use insulin and it affects over 29 million Americans. With new epigenetic research, however, the disease may be mitigated with a simple blood test that offers early knowledge and the possibility for pre-emptive lifestyle management. Lund University researchers in Sweden published their study in Nature Communications, in which they discovered a novel biomarker to predict a person’s risk of developing type 2 diabetes. By using a blood test to [more…]

Could Epigenetics Rescue Cognitive Impairment Caused by Getting Old?

May 10, 2016 Bailey Kirkpatrick

As we get older, our cognitive ability declines, especially our memory. Although aging-related cognitive impairment occurs naturally, humans have been fascinated since ancient times with uncovering a “fountain of youth” to ensure that our beauty, minds, and youthful qualities stay with us forever. What if we could stave off or protect our brain function as we age? With new research in epigenetics, we may be closer to finding out what’s behind memory loss and cognitive impairment. A study published in [more…]

Birth Season Could Epigenetically Determine Your Allergy Risk

April 5, 2016 Bailey Kirkpatrick

It has long been acknowledged that the season during which you were born can influence you throughout your life in many ways – your height, lifespan, and maybe even your temperament. In fact, research has found a strong connection between the season of someone’s birth and their personality. A study in European College of Neuropsychopharmacology found that people born in the summer are more likely to experience mood swings, those born in autumn are less likely to be depressive, and [more…]

Epigenetics: Feeding the Obesity and Diabetes Epidemic?

March 21, 2016 Bill Sullivan

Every kid reaching for the junk food has heard mom and dad’s warning, “You are what you eat!” But parents should be advised that children can now offer a humbling retort, “No, I’m what YOU ate!” A new study by scientists from the Institute of Experimental Genetics at Helmholtz Zentrum München (Neuherberg, Germany) suggests that the metabolic consequences of mom and dad’s dietary habits can be inherited by their kids via epigenetic mechanisms. So in addition to inheriting a genetic [more…]

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