Intended Epigenetic Drug Has Opposite Effect for Lung Cancer

February 26, 2019 WhatIsEpigenetics

Cancer is a complex disease influenced by numerous factors including genetic make-up, lifestyle, and the environment. Over the years, the growing field of epigenetics has greatly contributed to our understanding of cancer and tumor progression. It has also led to the development of novel drug therapies. Yet, despite the fact that epigenetic regulators have become attractive anticancer targets, many scientists believe that extra caution should be taken when assessing their overall effects. In a new study, one potential epigenetic therapy [more…]

Chromatin Immunoprecipitation Study Supports HDAC Inhibitor as Possible Lung Cancer Treatment

July 28, 2015 Bailey Kirkpatrick

A person’s genetic code can contribute to their risk for developing non-small cell lung cancer (NSCLC), which accounts for about 85% of lung cancers. Epigenetics, the study of chemical tags that impact gene expression without altering the genetic sequence, is shown to also profoundly influence the development of cancer. In a study by Asan Medical Center researchers from The University of Ulsan College of Medicine in Korea, chromatin immunoprecipitation (ChIP)-on-chip assays and other techniques were used to investigate the epigenetic [more…]

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