Epigenetic Study Unveils Vital Role of Housekeeping Genetic Elements and Potential for Cancer Therapy

January 9, 2024 Natalie Crowley

Advancements in technology have opened doors for scientists to delve deep into the complex world of genetic control elements, unveiling the intricate mechanisms governing gene activation within our genetic code. Contrary to the simplistic perception of cis-regulatory elements (CREs) as mere genetic on/off switches, emerging evidence underscores their capacity for nuanced behaviors. They’re not just toggles for gene enhancement; they orchestrate complex functions pivotal to sustaining cellular health. New research originating from Japan has uncovered about 11,000 significant genetic switches, [more…]

Histone Demethylation Plays a Role in Turning Stem Cells into Blood Vessel Cells

July 7, 2015 Bailey Kirkpatrick

How stem cells become specific cell types is an intricate process, yet understanding the mechanisms that trigger this process may well prove to be beneficial for use in repairing and regenerating tissue.  In a recent study, scientists at the University of Illinois at Chicago investigated the molecular mechanism, histone demethylation, and how it plays an essential role in mediating the conversion of stem cells into mature endothelial cells, which then produce blood vessels. Their findings, recently published in Stem Cell [more…]

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