epigenetics Archives | What is Epigenetics?

Cannabis Use Leaves a Lasting Mark on the Epigenome

October 22, 2024 Natalie Crowley

With the rising prevalence and legalization of cannabis worldwide, understanding its biological impact—especially on mental health—has become increasingly urgent. Research indicates that heavy use of high-potency cannabis significantly heightens the risk of mental health disorders. Factors such as starting at a young age and daily consumption further exacerbate this risk, underscoring the need for greater awareness of the potential consequences of cannabis use. Recent research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and the [more…]

Chronic Hepatitis C Leaves Lasting Epigenetic Scars

August 13, 2024 Natalie Crowley

Hepatitis C is a silent yet formidable liver infection caused by the hepatitis C virus (HCV). Unlike its acute form, which often resolves on its own, chronic hepatitis C persists, potentially leading to severe liver damage, including cirrhosis and cancer. While groundbreaking advancements in direct-acting antiviral (DAA) treatments have revolutionized HCV management, achieving high cure rates, the battle isn’t entirely won. Emerging research indicates that the virus leaves a lasting imprint on the immune system, even after successful treatment. In [more…]

Synergistic Epigenetic Medications Show Promise in Colorectal Cancer and Beyond

July 12, 2024 Natalie Crowley

Colorectal cancer ranks as the second leading cause of cancer-related deaths in the United States, presenting a multifaceted challenge influenced by both genetic and environmental factors. Despite advancements in treatment, there remains a pressing need for innovative therapies, particularly as cases rise among younger adults and at advanced disease stages. One promising approach lies in epigenetics, the study of chemical modifications on DNA and its packaging proteins that influence gene expression without altering the DNA sequence. Cancer cells often display [more…]

Artificial Intelligence and GPT-Powered Skin Epigenetics: Applications in Personalized Skincare

May 7, 2024 WhatIsEpigenetics

Epigenetics refers to the modifications of DNA by adding chemical tags, which switch genes on and off without altering the underlying DNA sequence. This process, known as epigenetic regulation, occurs in every person and changes throughout their life. Notably, skin aging, health, and beauty are influenced by environmental interactions, and these changes are governed by epigenetics rather than genes alone. Thus, epigenetic regulation is a pivotal factor in controlling one’s skin aging, health, and beauty status, offering dynamic and reversible [more…]

Researchers Unlock the Mysteries of Epigenetic Inheritance

April 30, 2024 Natalie Crowley

Understanding trait inheritance is crucial for unraveling the complexities of life’s blueprint and how it shapes the world around us. It provides insights into the transmission of characteristics from one generation to the next, shedding light on the mechanisms that underpin biological diversity and evolution. In a groundbreaking study featured in the journal Nature, researchers have unveiled the hidden secrets of how our DNA replication machinery meticulously safeguards and transfers epigenetic information during cell division. Led by Professor Yuanliang Zhai [more…]

Common Flame Retardant Alters the Epigenome of Aquatic Organisms

April 16, 2024 Natalie Crowley

Flame retardants are ubiquitous chemicals added to numerous consumer products to prevent the spread of fire. While they are essential in enhancing fire safety, their widespread use has raised concerns about their environmental and health impacts. One such flame retardant, triphenyl phosphate (TPhP), has gained popularity as an alternative to previously restricted compounds. However, recent studies suggest that TPhP may pose risks to both aquatic ecosystems and human health through its potential to disrupt endocrine systems and alter gene expression. [more…]

Epigenetic Changes in Immune Cells Linked to Alzheimer’s Disease

April 2, 2024 Natalie Crowley

Alzheimer’s disease is a degenerative brain disorder that impacts millions globally. While the exact cause of the disease is still unknown, a recent study by Northwestern University (NU) has shed light on the potential role of epigenetic modifications in the immune system of Alzheimer’s patients. The study found that Alzheimer’s patients experience epigenetic changes in their blood’s immune system, which could be influenced by environmental factors, past infections, and lifestyle behaviors. These findings could pave the way for the development [more…]

DNA Methylation’s Role in Preventing Cleft Lip and Palate

March 5, 2024 Natalie Crowley

Cleft lip and palate stand out as the most prevalent craniofacial birth anomalies worldwide, affecting approximately 1 in 700 newborns. Despite extensive research spanning decades, the precise etiology of most cases remains elusive, as does effective preventive measures. Understanding the causes of this abnormality has mainly focused on genetic factors, revealing numerous risk loci along the DNA, although direct causative variants are rare. Therefore, it is thought that this defect arises from a mix of genetic and environmental factors. Yet, [more…]

Scientists Use Machine Learning to Develop an Epigenetic Clock for Predicting Biological Age Better

February 20, 2024 Natalie Crowley

In the quest to unravel the mysteries of aging, scientists have long turned to our genetic code for answers. While machine learning models have offered insights into predicting biological age, understanding the causal factors behind aging has yet to be discovered. However, a groundbreaking study has now shed light on the hidden workings of aging by delving deep into the intricate realm of epigenetics. Scientists at Brigham and Women’s Hospital, part of Mass General Brigham, have developed an innovative “epigenetic [more…]

Type 2 Diabetes Linked with Epigenetic Changes

February 6, 2024 Elizabeth Fontanilles

Diabetes is a widespread health issue that affects millions of people worldwide. The disease is complex and can develop due to a combination of genetic and lifestyle factors. Given its increasing prevalence, scientists worldwide are investigating the underlying genetic complexities and epigenetic factors of diabetes in more detail. One question that researchers are interested in is whether epigenetic changes cause type 2 diabetes or if the changes occur only after a person has become ill. A new study by Lund [more…]

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