Could a New Epigenetic Blood Test Predict Your Risk of Type 2 Diabetes?

May 17, 2016 Bailey Kirkpatrick

Diabetes is a disease characterized by the body’s inability to properly use insulin and it affects over 29 million Americans. With new epigenetic research, however, the disease may be mitigated with a simple blood test that offers early knowledge and the possibility for pre-emptive lifestyle management. Lund University researchers in Sweden published their study in Nature Communications, in which they discovered a novel biomarker to predict a person’s risk of developing type 2 diabetes. By using a blood test to [more…]

Mitochondrial DNA Methylation Gives Clues to Insulin Response in Pre-Diabetics

September 1, 2015 Bailey Kirkpatrick

What if those who are resistant to insulin but don’t have diabetes could help prevent themselves and others from developing the disease? Researchers from Virginia Tech have discovered a biomarker in those who are pre-diabetic that could prevent them and potentially others from getting type 2 diabetes. The researchers uncovered that pre-diabetics, or people who are at high risk of developing type 2 diabetes, who do not respond to insulin had altered DNA in their mitochondria and had an increased [more…]

Type 2 Diabetes Mellitus and Epigenetics

April 7, 2015 Mary Vagula

Type 2 diabetes mellitus (T2DM) is a polygenic metabolic disease characterized by elevated blood sugar levels due to pancreatic beta-cell functional impairment and insulin resistance in tissues such as skeletal muscle, adipose tissue and the liver (1). Millions of people around the globe are diagnosed with diabetes, and its incidence is estimated to double by 2030. It has become one of the most challenging public health issues of 21st century and the fifth leading cause of death worldwide (2). The [more…]