The Epigenetics of Autism Spectrum Disorder (ASD)

August 27, 2019 Laurel Fish

Autism spectrum disorder (ASD) comprises of a range of neurodevelopmental disorders characterised by social/communication deficits as well as repetitive/restrictive interests or behaviours. Currently, the exact causes of ASD symptomology is far from being understood. This is, in part, due to the complex and multifactorial nature of the disorder. Despite such complexities significant progress to understanding the disorder has been made over the past few decades. Currently, it is speculated that a combination of genetic susceptibility (such as possessing rare or [more…]

Social Deficits of Autism Reversed By Epigenetic Drug

July 31, 2018 Tim Barry

It is estimated that 1 in 59 children in the United States fall somewhere on the autism spectrum. Autism spectrum disorder  (ASD) is a developmental disorder that affects the nervous system and is characterized by challenges with speech, social skills and communication.  Many factors can determine a child’s predisposition to developing autism, such as genetic mutations during brain development, chemical imbalance, and certain genetic disorders like tuberous sclerosis  and fragile X syndrome. Autism has been an incredibly difficult disease to [more…]

Epigenetic Reprogramming Gone Awry in Embryo May Lead to Abnormal Adult Behavior

February 16, 2016 Bailey Kirkpatrick

Epigenetic reprogramming occurs to the developing mammalian zygote immediately after fertilization and is crucial for proper development. This reprogramming is defined as the erasure of epigenetic marks such as DNA methylation and histone modifications. Researchers continue to uncover new information about the changes made to epigenetic marks on the embryo’s epigenome. In fact, a new study has found that when the process of epigenetic reprogramming goes awry, it can have severe consequences later in development, for instance, leading to abnormal [more…]

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