4 Ways Epigenetics May Explain Why Love is Not So Crazy
…methylation state of DNA and an increase in histone acetylation lead to a gene expression cascade, resulting in an increase in the number of glucocorticoid receptors in the hippocampus brain…
Search Results for transgenerational and dna methylation
Cataloging DNA Methylation & Gene Expression in Children
…between DNA methylation levels and gene expression might help us better interpret epigenome-wide association studies and understand the biological processes leading to disease,” said ISGlobal researcher Mariona Bustamante who co-led…
Excess Stress Changes Marks on DNA and Could Epigenetically Harm Mental Health
…study, the researchers found genome-wide change in DNA methylation. The CS patients who were exposed to high amounts of cortisol had less DNA methylation overall compared to healthy individuals. DNA…
Does DNA Methyltransferase Control the Brain’s ‘Gender’?
…level of DNA methylation via whole-genome bisulfite sequencing. They reported that gonadal steroids in this particular area “reduce activity of DNA methyltransferase (Dnmt) enzymes, thereby decreasing DNA methylation and releasing…
New Link Found Between DNA Methyltransferase and Antidepressants
…his team members focused on human and animal cells and found that FKBP51 interacts with DNMT1 by reducing the DNA methyltransferase’s activity and thereby reducing total DNA methylation across the…
Curcumin May Alleviate Liver Damage Caused by Drug-induced Epigenetic Changes
…DNA methyltransferases (DNMTs) and methyl CpG binding domain proteins (MBDs) are two of its families of proteins. DNMT member, DNMT1, maintains DNA methylation patterns and genomic stability, whereas DNMT3a and…
Betaine Intake During Pregnancy May Epigenetically Effect Transcription
…were curious if betaine supplementation altered DNA methylation of promoter regions of the Igf2 gene, which are regions of the gene responsible for activating transcription. Usually, DNA methylation is associated…
Epigenetic Tags on Serotonin Transporter Gene Linked to Stress
…response to the same fearful and angry faces and analyzed serotonin transporter gene methylation using DNA from the blood of 96 adolescents. They found that the connection between methylation and…
An Epigenetic Link Between Memory Loss and Epilepsy
…processes such as learning and higher thinking. The researchers sought to investigate a possible link between DNA methylation and memory loss which occurs as a result of epileptic seizures. DNA…
Lazy Versus Active Lifestyle Preferences May Have Epigenetic Roots
…regulator through Agouti-related peptide (AgRP) neurons. DNA methylation is an epigenetic mechanism that involves the addition of a methyl group to the DNA by a DNA methyltranseferase (DNMT) enzyme, resulting…
