Epigenetics: Fundamentals
…DNA methylation. Immunity & Related Disorders. There are several pieces of evidence showing that loss of epigenetic control over complex immune processes contributes to autoimmune disease. Abnormal DNA methylation has…
Search Results for dna methylation
Affectionate Moms with Depression May Epigenetically Buffer Their Child from Stress
…Select the ideal DNA bisulfite conversion kit and begin your DNA methylation research today! Previous research has demonstrated that there’s often an increase in DNA methylation and a decrease in…
Time Off Reverses the Adverse Epigenetic Effects of Shift Work Disorder
…DNA methylation patterns. Their results were published in the open-access online journal, Scientific Reports. DNA methylation is one of several epigenetic mechanisms that play a critical role in regulating gene…
Using CRISPR/Cas9 to Epigenetically Activate or Deactivate Genes
…DNA methylation, histone modifications, and non-coding RNA. The most well studied and abundant of these is DNA methylation, which includes the addition of a chemical group to DNA. Prior studies…
Epigenetics, Nutrition, and Our Health: How What We Eat Could Affect Tags on Our DNA
…attachment of a methyl group to DNA by an enzyme called DNA methyltransferase (DNMT), which stifles gene expression. New research links the Western Diet to changing DNA methylation levels in…
Nut Consumption Improves Sperm Parameters and May Alter Epigenome
…DNA methylation in sperm or methylation of specific features of the genome including CpG islands, non-CpG loci, and gene bodies. However, regional differences in DNA methylation were detected; 36 genetic…
Down a Path of Epigenetic Destruction: Smoking Cigarettes Adjusts Critical Marks on DNA
…previously shown that EZH2 and its effects are indicators that come before abnormal DNA methylation in genes. DNA methylation is a popular epigenetic mechanism that entails the addition of a…
Father’s Exposure to Phthalates Impact Epigenetic Marks on Sperm DNA
…they performed DNA methylation analyses on sperm cells to examine statistical associations. According to Wu, the researchers extracted DNA and analyzed around 485,000 sites for DNA methylation changes. Overall, they…
Histone Modifications
…control or regulate DNA methylation through chromatin-dependent transcriptional repression or activation. In the cell nucleus, when histone methylation occurs, specific genes within the DNA complexed with the histone may be…
Paternal Exercise Epigenetically Enhances Expression and Inheritance of a Key Gene Involved in Learning and Memory
…and histone acetylation as having opposing effects: DNA methylation represses gene expression, while histone acetylation promotes gene expression. A class of enzymes called DNA methyltransferases (DNMTs) catalyzes methylation of DNA…
