Epigenetic Regulation of a Single Gene Controls Drug and Stress Responses

December 2, 2014 Bailey Kirkpatrick

Researchers have found that the regulation of a specific gene located in an area of the brain linked to depression and drug addiction can reduce the way someone responds to drugs and stressful situations. A mouse study that focused on the epigenetic regulation of a single gene was carried out at the Icahn School of Medicine at Mount Sinai and was recently published in Nature Neuroscience. Earlier research supports a connection between epigenetic regulation and diseases related to depression and [more…]

Epigenetic Tags on Serotonin Transporter Gene Linked to Stress

August 6, 2014 Bailey Kirkpatrick

A new study offers an epigenetic explanation as to why some people are more reactive to stress or more vulnerable to disorders related to stress. A team of researchers at Duke University have found that methylation of a gene linked to post-traumatic stress disorder (PTSD) and clinical depression can affect how an individual reacts to threats or stress. Recently published online in the journal Nature Neuroscience, the results highlight the link between the common epigenetic mechanism of DNA methylation and [more…]

“I Am No Longer Haunted By That Awful Memory” – New Epigenetic Drug Treatment May Erase Painful Memories

January 27, 2014 Milka Rodriguez

 Is it possible for a drug to dampen a traumatic memory? It may be, as researchers are discovering that a fundamental epigenetic mechanism is responsible for long-term fear memory. Neuroplasticity, also called brain plasticity, refers to the changes in neural connections such as synapses and neural pathways as a result of changes in behavior, environmental exposure and neural processes (1,2).  While it was once believed that the brain is a physiologically static organ and its networks were fixed, research over [more…]

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