Sequence-specific microscopic visualization of DNA methylation status at satellite repeats in individual cell nuclei and chromosomes

13 years ago

Scientists from Japan developed methylation-specific fluorescence in situ hybridization (MeFISH) for microscopic visualization of DNA methylation status at specific repeat…

Targeting Noncoding RNAs in Disease: Challenges and Opportunities

13 years ago

Noncoding RNAs make up the majority of transcribed RNA and have a wide range of functions in cellular and developmental…

Research in Epigenetics Experiencing Exponential Growth

13 years ago

Publication growth in epigenetic-related research attests to the exponential expansion of this field since 2000 according to GENRports (GENReports: Market…

Illumina Doubles Output of Benchtop Sequencer MiSeq to 15 Gb

13 years ago

San Diego-based Illumina, Inc. doubles the sequencing output of its benchtop sequencer MiSeq to 15 gigabases (Gb) by increasing the…

Identifying Site Specific Methylation in tRNAs and Target Substrates of RNA Methyltransferase NSun2

13 years ago

Currently, DNA methylation is one of the most broadly studied and well-characterized epigenetic modifications associated with gene silencing. The biological…

System for Optical Control of Mammalian Endogenous Transcription and Epigenetic States

13 years ago

Robust and versatile technologies that enable optical modulation of transcription in the mammalian endogenous genome have been difficult to achieve…