The scientists at Johns Hopkins University used a genome-wide pharmacologic transcriptome approach to identify two novel cancer-specific DNA methylation markers…
Researchers at Epigentek recently developed a new and breakthrough approach to identify the "fifth base" of RNA, N6-methyladenosine (m6A) to…
The scientists at MIT describe an approach for efficient targeted demethylation of specific CpGs in human cells using fusions of…
5-methylcytosine is found in the context of paired symmetrical methylation of a CpG site. In normal somatic cells, most CpG…
In their studies, the scientists at Beckman Research Institute of City of Hope demonstrated that Ten eleven translocation (TET) enzymes…
Scientists at Epigentek developed a series of new products for DNA library preparation used in next generation sequencing analysis of…
The scientists from A*STAR's Institute of Medical Biology (IMB) and Institute of Molecular and Cell Biology (IMCB) developed a novel…
A new study from the scientists at the University of Southern California (USC) describes for the first time how natural…
To form chromatin, DNA is tightly wrapped around nuclear proteins called histones. The repeating DNA-histone complex, which consists of 146…
In human DNA, 5-methylcytosine is found in approximately 1.5% of genomic DNA. In somatic cells, 5-mC occurs almost exclusively in…