DNMT1-Interacting RNAs Block Gene-Specific DNA Methylation

12 years ago

5-methylcytosine is found in the context of paired symmetrical methylation of a CpG site. In normal somatic cells, most CpG…

A New Study Shows MicroRNA-26a Targets DNA Demethylation Enzymes

12 years ago

In their studies, the scientists at Beckman Research Institute of City of Hope demonstrated that Ten eleven translocation (TET) enzymes…

“Post-Bisulfite” and Higher Sensitivity DNA Library Preparation Technology for Epigenetics-Targeted Next Generation Sequencing Analysis

12 years ago

Scientists at Epigentek developed a series of new products for DNA library preparation used in next generation sequencing analysis of…

Novel Assay to Probe the DNA Methylation State of Multiple Genomic Loci in Single Cells

12 years ago

The scientists from A*STAR's Institute of Medical Biology (IMB) and Institute of Molecular and Cell Biology (IMCB)  developed a novel…

New Study Shows Epigenetic Process Controls Cancer-Killing Cells

12 years ago

A new study from the scientists at the University of Southern California (USC) describes for the first time how natural…

Chromatin Remodelers Fine-Tune H3K36me-Directed Deacetylation of Neighbor Nucleosomes by Rpd3S

12 years ago

To form chromatin, DNA is tightly wrapped around nuclear proteins called histones. The repeating DNA-histone complex, which consists of 146…

Epigenetic Memory at Embryonic Enhancers Identified in DNA Maps from Adult Mouse Tissues

12 years ago

In human DNA, 5-methylcytosine is found in approximately 1.5% of genomic DNA. In somatic cells, 5-mC occurs almost exclusively in…

Sequence-specific microscopic visualization of DNA methylation status at satellite repeats in individual cell nuclei and chromosomes

12 years ago

Scientists from Japan developed methylation-specific fluorescence in situ hybridization (MeFISH) for microscopic visualization of DNA methylation status at specific repeat…

Targeting Noncoding RNAs in Disease: Challenges and Opportunities

12 years ago

Noncoding RNAs make up the majority of transcribed RNA and have a wide range of functions in cellular and developmental…

Research in Epigenetics Experiencing Exponential Growth

13 years ago

Publication growth in epigenetic-related research attests to the exponential expansion of this field since 2000 according to GENRports (GENReports: Market…