Stem/Early Progenitor Cell Commitment is Directed by Hydroxymethylation at Gene Regulatory Regions During Erythropoiesis

13 years ago

Hematopoietic stem cells (HSCs) are rare bone marrow cells that have self-renewal capability and are multipotent. Upon differentiation, HSCs become…

Our Parents’ Lives Could Influence Memories Through Epigenetics

13 years ago

The scientists at Emory University School of Medicine showed new evidence that our parents’ behaviors before we are born may…

Folate Deficiency in a Father’s Diet Could Cause Negative Pregnancy Outcomes by Changing Sperm Epigenome

13 years ago

Scientists at McGill University, Canada reported that folate deficiency in a father’s diet could increase birth defects in the offspring…

mRNA Stability Is Regulated By Dynamic m6A RNA Methylation

13 years ago

Messenger RNA (mRNA) is a single-stranded RNA molecule that is essential in mediating the transfer of genetic information from DNA…

Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis Revealed by High-Resolution Mapping

13 years ago

In eukaryotic RNA, the methylation of adenosine at the N6 position to form N6-methyladenosine (m6A) is the most common and…

The Epigenetic Landscape is a Key Determinant of Gene Expression Reprogramming in Cardiac Hypertrophy

13 years ago

The epigenetic signature for cardiac hypertrophy, which can progress to heart failure through an adaptive response of the myocardium to…

Transposase-Accessible Chromatin Assay for Fast and Sensitive Epigenomic Profiling

13 years ago

Scientists at Stanford University School of Medicine have developed a rapid and sensitive method for integrative epigenomic analysis called assay…

RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock

13 years ago

Circadian rhythms are the physiological changes that follow a roughly 24-hour cycle, such as the sleep-wake cycle. They are found…

Accurately Telling the Age of Human Tissues and Cells by DNA Methylation Clock

13 years ago

External signs of the human body’s age can be given by wrinkles and graying hair. However, these signs may not…

Vitamin C Modulates TET1 Function During Somatic Cell Reprogramming

13 years ago

Cellular reprogramming of somatic cells to a pluripotent state (an undetermined state in which a cell is capable of differentiating…